Acute renal failure in cardiac surgical patients, potentiated by gentamicin and calcium

Anaesthesia and Intensive Care
M SchneiderJ Peacock

Abstract

A retrospective study in coronary artery bypass graft patients was undertaken to assess the effect of gentamicin and a bypass prime with a high calcium on the incidence of renal failure. Patients who received both Haemaccel (polygeline, Hoechst Marion Roussel) (calcium concentration 6.25 mmol/l) in the bypass prime and gentamicin perioperatively had a higher incidence of renal failure compared with those who received only Haemaccel (P = 0.005), only gentamicin (P = 0.002) or neither (P = 0.0001). We suggest that the combination be avoided in this group of patients.

References

Jan 1, 1992·Circulation Research·R A Zager
Feb 1, 1988·The Journal of Clinical Investigation·P D Walker, S V Shah
Nov 1, 1986·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J M Weinberg
Jun 1, 1993·Anaesthesia and Intensive Care·S ValentineJ Peacock

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Citations

Jul 9, 2016·The Annals of Pharmacotherapy·Ryan M RivosecchiSandra L Kane Gill
May 26, 2006·European Journal of Anaesthesiology·I J Davidson

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