PMID: 1192623Nov 1, 1975Paper

Acute renal failure secondary to ureteral fungus ball obstruction in a patient with reversible deficient cell-mediated immunity.

Clinical Nephrology
D L LevinJ G Porush

Abstract

A patient with a single functioning kidney and anuria due to ureteropelvic obstruction by a Candida fungus ball is described. During treatment with amphotericin B administered via a nephrostomy tube the drug was not detected in the serum, indicating that absorption from urothelium was not significant. Immunological studies demonstrated a lack of cell-mediated immunity which was probably brought about by a long course of prednisone and later restored when this drug was discontinued. This immunosuppression was evident even with a relatively small dosage of prednisone (5 mg daily). The literature concerning renal candidiasis and predisposing factors is reviewed.

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