Acute renal function deterioration in a Coronary Unit in Spain

Medicina intensiva
D MartíE Asín

Abstract

To assess the incidence and prognostic value of acute renal function deterioration (ARFD) in patients with acute heart disease. Coronary Care Unit in a tertiary university hospital. Retrospective study. One hundred consecutive patients admitted during 2004. No randomized interventions were done. Diagnostic and therapeutic procedures were performed according to local protocols and current Clinical Practice Guidelines. PRIMARY VARIABLES: The primary aim of the study was to analyze the incidence of acute renal function deterioration and its effect in mortality during hospitalization. ARFD was defined as the increase of serum creatinine by 0.5 mg/dl and/or by 50% over baseline. Incidence of ARFD was 26%, with a mean increase of serum creatinine of 1.5 +/- 0.9 mg/dl. ARFD was significantly associated with age, background of hypertension and chronic kidney disease. Patients with ARFD had a more complicated course, longer hospitalizations, and received fewer catheterisms. Acute renal function deterioration was associated with higher mortality during hospitalization (33% versus 6%, p = 0.002). Acute renal function deterioration is frequent in patients with acute heart disease and its presence is linked with higher mortality.

References

Sep 17, 1998·The New England Journal of Medicine·C A HerzogA J Collins
Jul 15, 1999·Journal of the American Society of Nephrology : JASN·P S Parfrey, R N Foley
Sep 15, 2000·Journal of the American College of Cardiology·P A McCulloughS Borzak
Aug 21, 2002·Circulation·Jassim Al SuwaidiUNKNOWN PARAGON-A Investigators. Platelet IIb/IIIa Antagonism for the Reduction of Acute coronary syndrome events in a Global Organi
Nov 27, 2002·The American Journal of Cardiology·James L JanuzziUNKNOWN TACTICS-TIMI 18 Investigators
Jun 5, 2003·Annals of Internal Medicine·Michael G Shlipak
Aug 18, 2004·Critical Care : the Official Journal of the Critical Care Forum·Rinaldo BellomoUNKNOWN Acute Dialysis Quality Initiative workgroup
Sep 24, 2004·The New England Journal of Medicine·Nagesh S AnavekarMarc A Pfeffer
Dec 14, 2004·The American Journal of Cardiology·Raphaëlle DumaineUNKNOWN SYCOMORE Investigators
Dec 24, 2004·European Heart Journal·Lennart G BongartzBranko Braam
May 5, 2005·JAMA : the Journal of the American Medical Association·Ioannis IakovouAntonio Colombo
Aug 18, 2005·JAMA : the Journal of the American Medical Association·Shigehiko UchinoUNKNOWN Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators
Jan 3, 2006·Journal of the American College of Cardiology·Robert W Schrier
Sep 5, 2006·Medicina intensiva·M E Herrera-GutiérrezUNKNOWN Grupo de trabajo "Estado actual del fracaso renal agudo y de las técnicas de reemplazo renal en UCI. Estudio FRAMI"

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Minerva urologica e nefrologica = The Italian journal of urology and nephrology
M DoglianiR Andrini
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
P J ConlonK Landolfo
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
J M SungJ J Huang
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Daniel HeiseMichael Quintel
© 2022 Meta ULC. All rights reserved