Acute resistance exercise does not change the hormonal response to sublingual androstenediol intake.

European Journal of Applied Physiology
G A Brown, Drew McKenzie

Abstract

Sublingual intake of 21.4 mg androstenediol increases serum testosterone concentrations whereas swallowing 200 mg androstenediol does not. The duration of increase in serum testosterone following sublingual androstenediol (SL-DIOL) is unknown. Resistance exercise (EX) following SL-DIOL may cause larger increases in serum estradiol concentrations than while at rest. This project evaluated the duration of change in, and the effects of acute EX on, the hormonal response to SL-DIOL. Six young resistance trained males consumed either placebo (PL) or SL-DIOL before a single session of EX or no exercise (Rest) in a random, double blind, crossover manner (for a total of four trials). Blood samples were collected before supplementation, and at 60, 120, 180, 240, 480, and 720 min post-supplementation, with the exercise occurring between 60 and 120 min. The serum [total testosterone] increased (P < 0.05) at 60 min similarly in SL-DIOL-EX and SL-DIOL-Rest by approximately 115%, and at 120 min by approximately 107% with no differences due to exercise. The serum [estradiol] increased (P < 0.05) similarly in SL-DIOL-EX and SL-DIOL-Rest by approximately 33% at 60 min and approximately 45% at 120 min, with no differences due to exercise. Serum ...Continue Reading

References

Jan 1, 1978·The Journal of Clinical Endocrinology and Metabolism·C LongcopeS E Fineberg
Oct 1, 1975·The Journal of Clinical Endocrinology and Metabolism·R HortonM Cosgrove
May 1, 1992·Archives of Andrology·S VillalpandoV Cortés-Gallegos
Oct 1, 1990·Journal of Applied Physiology·W J KraemerS J Fleck
Mar 5, 1990·Molecular and Cellular Endocrinology·G D BerkovitzC J Migeon
Oct 1, 1988·Medicine and Science in Sports and Exercise·W J Kraemer
Jan 1, 1985·European Journal of Applied Physiology and Occupational Physiology·T A Cadoux-HudsonF J Imms
Jan 1, 1985·European Journal of Applied Physiology and Occupational Physiology·C LupoG Carli
Jan 1, 1973·Acta Medica Scandinavica·P Lundbergh, T Strandell
Aug 1, 1967·Acta Endocrinologica·J BlaquierR I Dorfman
Dec 1, 1969·The Journal of Clinical Investigation·C LongcopeR Horton
Nov 1, 1980·The Journal of Clinical Endocrinology and Metabolism·H K KleyH L Krüskemper
Aug 1, 1993·Journal of the American College of Cardiology·E D Frohlich
Jul 4, 1996·The New England Journal of Medicine·S BhasinR Casaburi
Mar 1, 1997·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·I FyssasB C Golematis
Jul 23, 1999·Medicine and Science in Sports and Exercise·M D Delp
Dec 22, 1999·Journal of Applied Physiology·G A BrownD S King
Jan 14, 2000·The Journal of Clinical Endocrinology and Metabolism·B B RasmussenR R Wolfe
Jan 19, 2000·European Journal of Applied Physiology·C P EarnestS G Beckham
Feb 22, 2000·JAMA : the Journal of the American Medical Association·B Z LederJ S Finkelstein
Feb 23, 2000·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·C S BallantyneJ D MacDougall
Sep 21, 2000·International Journal of Sport Nutrition and Exercise Metabolism·G A BrownD S King
May 8, 2001·Psychotherapy and Psychosomatics·G KanayamaJ I Hudson
Oct 17, 2001·Journal of the American College of Nutrition·G A BrownD S King
Nov 8, 2001·Metabolism: Clinical and Experimental·J S VolekW J Kraemer
Dec 1, 2001·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·G A BrownD S King
Feb 8, 2002·American Journal of Physiology. Endocrinology and Metabolism·Arny A FerrandoRandall J Urban
Mar 16, 2002·Journal of Applied Physiology·Michael D BrownMark A Supiano
Sep 30, 2003·Journal of Applied Physiology·Mark S TremblayWalter Van Helder

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Citations

Aug 3, 2018·Journal of the International Society of Sports Nutrition·Chad M KerksickRichard B Kreider

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