Acute right ventricular failure in the setting of acute pulmonary embolism or chronic pulmonary hypertension: a detailed review of the pathophysiology, diagnosis, and management.

Current Cardiology Reviews
Jennifer Cowger Matthews, Vallerie McLaughlin

Abstract

The right ventricle (RV) is integral to normal cardiac function, but receives little attention in the medical literature. The etiologic causes of acute RV failure often differ from those encountered in left ventricular dysfunction. Thus, RV failure frequently requires diagnostic procedures and management strategies that differ from those routinely used in the management of intrinsic left ventricular dysfunction. In this summary, the structure and function of the RV will be reviewed, concentrating on the pathophysiologic mechanisms behind the development of RV dysfunction. We will then focus on two distinct populations of patients who are at risk for acute RV failure: those with chronic pulmonary arterial hypertension (PAH) and those with acute pulmonary embolism. In chronic PAH, we will examine clinical circumstances common to hospitalized patients that may provoke acute RV decompensation, as well as pharmacologic therapies that are unique to RV failure management in PAH. Individuals with acute RV failure in the setting of pulmonary embolism represent a group with particularly high mortality, and the specific diagnostic and management strategies that are important for improved survival will be discussed.

Citations

Oct 12, 2012·Medizinische Klinik, Intensivmedizin und Notfallmedizin·J SchmidtM Christ
Feb 21, 2013·Annals of Biomedical Engineering·Alessandro Bellofiore, Naomi C Chesler
Jul 24, 2008·Current Treatment Options in Cardiovascular Medicine·Jennifer Cowger MatthewsKeith D Aaronson
Apr 12, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Matthias ThielmannHeinz Jakob
Jun 28, 2011·American Journal of Respiratory and Critical Care Medicine·Marius M Hoeper, John Granton
Nov 5, 2013·Thrombosis Research·Alexander T CohenMeredith M P Gurwith
Nov 27, 2015·Pulmonary Pharmacology & Therapeutics·Poorella LingeshwarKashif Hanif
Sep 27, 2012·Progress in Cardiovascular Diseases·Hooman D Poor, Corey E Ventetuolo
Jan 27, 2015·The Clinical Respiratory Journal·Franco Piovella, Diana Irina Iosub
Jun 20, 2014·Heart and Vessels·Karsten KellerJörn Oliver Balzer
Apr 24, 2015·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·M Kennedy HallChris L Moore
Aug 1, 2015·Emergency Medicine Clinics of North America·John C Greenwood, Ryan M Spangler
Mar 10, 2015·The American Journal of Medicine·Scott J CameronHanna Mieszczanska
Mar 29, 2014·Journal of Cardiothoracic and Vascular Anesthesia·Leila Hosseinian
Apr 4, 2015·Current Hypertension Reports·Jonathan Grinstein, Mardi Gomberg-Maitland
May 7, 2013·Journal of Cardiothoracic and Vascular Anesthesia·Amy C Robertson, Susan S Eagle
Apr 4, 2015·The Canadian Journal of Cardiology·John J RyanStephen L Archer
Nov 5, 2014·High Altitude Medicine & Biology·Harvey V Lankford, Erik R Swenson
May 30, 2016·Mayo Clinic Proceedings·Clarence T LiCrystal R Bonnichsen
Jun 1, 2016·Medizinische Klinik, Intensivmedizin und Notfallmedizin·T KrammE Mayer
Jul 10, 2016·The American Journal of Medicine·Hem DesaiJoseph S Alpert
Sep 27, 2016·European Journal of Radiology·Saeed MirsadraeeEdwin J van Beek
Oct 30, 2016·The American Journal of Emergency Medicine·James DaleyChristopher L Moore
Mar 27, 2018·Pulmonary Circulation·Valentina MercurioPaul M Hassoun
Mar 10, 2017·British Journal of Hospital Medicine·Timothy Shao Ern Tan, Saad Ahmad
Oct 7, 2017·Anesthesiology·George J Crystal, Paul S Pagel
Sep 6, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Shadi LahhamLishi Zhang
Jan 5, 2014·Journal of the American Heart Association·Erin M HaldJohn-Bjarne Hansen
Sep 13, 2018·European Journal of Preventive Cardiology·Laura Verbree-WillemsenDiederick E Grobbee
Dec 2, 2015·European Respiratory Review : an Official Journal of the European Respiratory Society·Ekkehard Grünig, Andrew J Peacock
Oct 12, 2018·Current Cardiology Reviews·Mario NaranjoJanani Rangaswami
Jul 18, 2019·Current Opinion in Pulmonary Medicine·Joanne A GroeneveldtBerend E Westerhof
Jun 20, 2019·The Medical Journal of Australia·Paul C KrugerGraeme J Hankey
Feb 20, 2020·JAMA Cardiology·Monica M Parks
Mar 14, 2020·AACN Advanced Critical Care·Barbara Leeper
Apr 7, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Cameron Dezfulian
May 17, 2019·Anesthesiology·Thomas LangerAntonio Pesenti

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