Acute transverse myelopathy and cutaneous vasculopathy in primary Sjögren's syndrome

European Neurology
R K LyuT C Chen

Abstract

Neurologic complications of primary Sjögren's syndrome (SS) may be under-estimated. Here, we report a patient with primary SS, who developed acute transverse myelopathy (ATM) and skin purpuric lesions simultaneously. In the first episode of myelopathy, the patient's neurologic deficits improved after steroid therapy. However, she died of recurrent myelopathy with systemic complications 4 months later. Review of the English-language literature revealed only 3 cases of primary SS associated with ATM, none of the 3 patients had skin lesions. Anti-Ro(SS-A) antibodies, and ATM in our patient suggests that immune-mediated vasculopathy may play a role in the pathogenesis of acute myelopathy in primary SS.

Citations

Aug 10, 2000·Journal of the Neurological Sciences·Y ManabeK Abe
May 26, 1998·Journal of the Neurological Sciences·I NakashimaY Itoyama
Sep 6, 2003·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Serge PerrotAnne-Geneviève Marcelin
Apr 5, 2012·Autoimmune Diseases·Gabriel J TobónPierre Youinou
Apr 21, 2009·Medicina clínica·Marta RamírezFrancesc Graus

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