Acute Treatment Therapies for Pediatric Migraine: A Qualitative Systematic Review

Headache
Irene R Patniyot, Amy A Gelfand

Abstract

We sought to conduct a qualitative systematic review to evaluate the safety and efficacy of available treatments for pediatric patients with migraine or benign primary headache in the emergency department, in an effort to inform future practice. Scopus, Medline, and PubMed databases were searched for randomized controlled trials retrospective reviews, review articles, and case studies discussing migraine or benign primary headache management that were conducted in the emergency room or outpatient acute care setting in pediatric patients (less than 18-years old). Meeting abstracts and cited references within articles were also evaluated. Multiple variables were recorded, including type of treatment, study design, dosing, primary outcome, and side effects. Therapeutic gain was calculated in studies with a placebo arm. Treatments were subjectively assessed based on methodology and number of trials for a particular therapy. Thirty-one studies were included in the final analysis. Of these, 17 were randomized controlled trials, 9 were retrospective reviews, and 5 were prospective chart review studies. One pertained to IV fluids, 2 to nonspecific analgesic use, 5 to dopamine receptor antagonists, 2 to valproic acid, 1 to propofol, 1 t...Continue Reading

Associated Clinical Trials

Jun 14, 2017·Joseph (Tony) Zitek, MD

References

Feb 1, 1997·Pediatric Neurology·M L HämäläinenP R Santavuori
Apr 1, 1997·Cephalalgia : an International Journal of Headache·F M CutrerM A Moskowitz
Feb 13, 2001·Cephalalgia : an International Journal of Headache·P Tfelt-HansenUNKNOWN International Headache Society Clinical Trials Subcommittee
Jun 22, 2002·Brain : a Journal of Neurology·Thorsten Bartsch, Peter J Goadsby
Jan 30, 2004·Annals of Emergency Medicine·David C BrousseauJames G Linakis
Mar 16, 2004·Proceedings of the National Academy of Sciences of the United States of America·Dan LevyRami Burstein
Nov 3, 2006·Headache·Joel R Saper, Stephen Silberstein
Apr 5, 2007·JAMA : the Journal of the American Medical Association·Jan Lewis BrandesShelly E Lener
Jul 4, 2007·Neurology·M E BigalUNKNOWN AMPP advisory group
Aug 3, 2007·Pediatrics·Donald W LewisUNKNOWN Adolescent Migraine Steering Committee
Jan 20, 2009·The Journal of Emergency Medicine·Evelyne D TrottierJocelyn Gravel
Feb 25, 2010·Pediatric Emergency Care·Larry B Mellick, Michelle R Pleasant
Jun 10, 2010·Pediatrics·Lawrence P RicherUNKNOWN Pediatric Emergency Research Canada Emergency Department Migraine Group
Feb 8, 2011·The American Journal of Emergency Medicine·Evelyne D TrottierAnne Lortie
May 11, 2011·Journal of Child Neurology·Geneviève LegaultMichael I Shevell
May 16, 2012·Pediatrics·Frederick J DerosierM Chris Runken
Jun 20, 2012·Cephalalgia : an International Journal of Headache·Tony W HoUNKNOWN Rizatriptan Protocol 082 Pediatric Migraine Study Group
Nov 29, 2012·Pediatric Emergency Care·David C SheridanGarth D Meckler
Apr 27, 2013·CNS Drugs·Stephen D Silberstein, Shashidhar H Kori
Jun 19, 2013·Cephalalgia : an International Journal of Headache·UNKNOWN Headache Classification Committee of the International Headache Society (IHS)
Nov 5, 2013·The Journal of Emergency Medicine·Emily GertschSita Kedia
Dec 18, 2013·Cephalalgia : an International Journal of Headache·Sita KediaScott W Powers
Feb 12, 2014·Headache·Jessica M Kanis, Nathan L Timm

❮ Previous
Next ❯

Citations

Jun 5, 2016·Paediatric Drugs·Benoit Bailey, Evelyne D Trottier
Jul 28, 2016·Expert Review of Neurotherapeutics·Ashish Dhir
Sep 7, 2016·The Journal of Headache and Pain·Noemi FaeddaVincenzo Guidetti
Jan 29, 2017·Expert Opinion on Pharmacotherapy·Amanda E Macone, Michael D Perloff
Nov 23, 2016·Current Pain and Headache Reports·Thyra LanghagenKlaus Jahn
Mar 7, 2018·Nursing·Kaitlyn E Sahd-Brown, Lisa A Ruth-Sahd
Aug 4, 2018·Continuum : Lifelong Learning in Neurology·Amy A Gelfand
Sep 21, 2018·Current Opinion in Pediatrics·Shalonda K SlaterHope L O'Brien
Feb 15, 2019·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Deborah I Friedman
Dec 7, 2019·Journal of Child Neurology·Clare E SkoraChris B Oakley
Jan 8, 2020·Research Quarterly for Exercise and Sport·Oscar García-GarcíaJosé López-Chicharro
Sep 23, 2020·Research Quarterly for Exercise and Sport·Gustavo Z Schaun, Cristine L Alberton
Feb 16, 2018·Pediatric Annals·Marina Khrizman, Ann Pakalnis
Aug 30, 2019·Developmental Medicine and Child Neurology·Paul E Youssef, Kenneth J Mack
Apr 18, 2017·Pediatric Annals·Heidi K Blume
Dec 12, 2018·Expert Opinion on Pharmacotherapy·P BarbantiG Egeo
Aug 3, 2019·Cephalalgia : an International Journal of Headache·Mario Fp PeresJosé Cipolla-Neto
Aug 9, 2020·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Nicole M AcquistoMichael C Thomas
Nov 25, 2020·Paediatric Drugs·Gregory L Holmes
Jan 14, 2020·Pediatric Emergency Care·David C SheridanGarth D Meckler
Jan 26, 2021·Pediatric Neurology·Nirupama KannikeswaranLalitha Sivaswamy
Aug 5, 2021·Pediatric Quality & Safety·Adam A VukovicEileen Murtagh-Kurowski
Aug 3, 2021·Current Problems in Pediatric and Adolescent Health Care·Debra M O'Donnell, Anastazia Agin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here