Acute vision loss after ocriplasmin use

Retinal Cases & Brief Reports
Benjamin ReissSam Mansour

Abstract

There have been reports in the literature of transient vision loss after ocriplasmin injection and ellipsoid layer disruption on spectral domain optical coherence tomography. The authors report a patient with transient vision loss and more prolonged ellipsoid layer dysfunction. The authors present a 55-year-old woman with vitreomacular traction and a small foveal schisis who received ocriplasmin injection and experienced sudden transient vision loss. Spectral domain optical coherence tomography imaging revealed significantly increased schisis, new subretinal cavity, and prolonged ellipsoid layer disruption at 9 months. Previous reports suggested that acute vision loss after ocriplasmin injection may be due to ellipsoid layer disruption. This case showed vision loss, which may due to increased foveal schisis and a new subretinal cavity on spectral domain optical coherence tomography imaging. There was little correlation between ellipsoid layer loss and visual function.

References

Aug 17, 2012·The New England Journal of Medicine·Peter StalmansUNKNOWN MIVI-TRUST Study Group
Jul 26, 2013·Ophthalmic Surgery, Lasers & Imaging Retina·Brian T KimJorge A Fortun
Dec 21, 2013·The British Journal of Ophthalmology·Rishi P SinghPeter K Kaiser

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Citations

May 4, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Irini ChatziralliPanagiotis Theodossiadis

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