Acylsugar Acylhydrolases: Carboxylesterase-Catalyzed Hydrolysis of Acylsugars in Tomato Trichomes

Plant Physiology
Anthony SchilmillerRobert L Last

Abstract

Glandular trichomes of cultivated tomato (Solanum lycopersicum) and many other species throughout the Solanaceae produce and secrete mixtures of sugar esters (acylsugars) on the plant aerial surfaces. In wild and cultivated tomato, these metabolites consist of a sugar backbone, typically glucose or sucrose, and two to five acyl chains esterified to various positions on the sugar core. The aliphatic acyl chains vary in length and branching and are transferred to the sugar by a series of reactions catalyzed by acylsugar acyltransferases. A phenotypic screen of a set of S. lycopersicum M82 × Solanum pennellii LA0716 introgression lines identified a dominant genetic locus on chromosome 5 from the wild relative that affected total acylsugar levels. Genetic mapping revealed that the reduction in acylsugar levels was consistent with the presence and increased expression of two S. pennellii genes (Sopen05g030120 and Sopen05g030130) encoding putative carboxylesterase enzymes of the α/β-hydrolase superfamily. These two enzymes, named ACYLSUGAR ACYLHYDROLASE1 (ASH1) and ASH2, were shown to remove acyl chains from specific positions of certain types of acylsugars in vitro. A survey of related genes in M82 and LA0716 identified another tric...Continue Reading

Citations

Sep 27, 2018·The Plant Journal : for Cell and Molecular Biology·Yang QuVincenzo De Luca
Oct 5, 2016·Bioscience, Biotechnology, and Biochemistry·Taiji Nomura
Oct 16, 2018·Frontiers in Plant Science·Stefan BennewitzAlain Tissier
Nov 25, 2018·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Ben VosmanRoeland E Voorrips
Jan 1, 2018·Euphytica; Netherlands journal of plant breeding·Ben VosmanRoeland E Voorrips
Apr 23, 2019·Current Opinion in Plant Biology·Pengxiang FanRobert L Last

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