PMID: 7011068Jan 1, 1981Paper

Adaptation of a Nigerian strain of Plasmodium falciparum to Panamanian Aotus trivirgatus

The American Journal of Tropical Medicine and Hygiene
R N RossanJ S Harper

Abstract

A patent infection (more than 190 days duration) with Plasmodium falciparum, obtained directly from a patient who had been exposed to malaria in Nigeria, was established in a splenectomized Panamanian owl monkey, Aotus trivirgatus griseimembra. Subinoculations from the original monkey recipient into one splenectomized and two normal A. t. griseimembra produced primary patient parasitemias of 18-54 days duration. These results represent the first successful adaptation of P. falciparum from man to a monkey of Panamanian origin.

Citations

Sep 1, 1987·The American Journal of Tropical Medicine and Hygiene·R N Rossan, D C Baerg

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