Adaptation of Addenbrooke's Cognitive Examination-Revised for the Greek population

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
E KonstantinopoulouN Taskos

Abstract

Addenbrooke's Cognitive Examination-Revised [1] is a highly sensitive and specific bedside test for the diagnosis of dementia. The aim of this study was to validate a Greek version of this simple, bedside instrument and to investigate its psychometric properties. We translated and administered the Greek version of the ACE-R to 95 individuals comprising two groups: a dementia group (n=35) and an age-matched and education-matched healthy control group (n=60). Our results suggest high internal consistency and very good sensitivity, specificity and negative predictive value, but only adequate positive predictive value for the ACE-R, with excellent diagnostic accuracy. In our sample, the ratio of verbal fluency plus language scores to orientation plus memory (VLOM) subscore failed to discriminate patients in the target dementia group. The present findings support the usefulness of the ACE-R as a brief dementia screening tool in clinical practice. Further neuropsychologic evaluation is required for the differential diagnosis of dementia.

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Citations

Sep 14, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A H Schapira, M Hillbom
May 24, 2012·Dementia and Geriatric Cognitive Disorders Extra·Kelssy Hitomi Dos Santos KawataEtsuro Mori
Nov 21, 2015·Journal of Clinical and Experimental Neuropsychology·Lambros MessinisPanagiotis Papathanasopoulos
Jul 31, 2016·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Antonieta NietoJosé Barroso
Feb 9, 2017·International Journal of Geriatric Psychiatry·Bian-Rong WangJian-Quan Shi
Feb 3, 2018·Dementia and Geriatric Cognitive Disorders·Yunier Broche-Pérez, Héctor Alejandro López-Pujol
Apr 11, 2018·Journal of Speech, Language, and Hearing Research : JSLHR·Vasiliki KoukouliotiPanagiotis Ioannidis
May 19, 2012·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Viviane Amaral-Carvalho, Paulo Caramelli
Dec 5, 2019·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Antonios MougiasAntonios Politis
Apr 2, 2011·Headache·Dimitris ParissisDimitris Karacostas
Apr 22, 2020·Journal of the International Neuropsychological Society : JINS·Panagiotis KourtesisSharon Abrahams
Sep 1, 2017·Journal of Neurology·Efstratios KaravasilisIoannis Seimenis
Dec 11, 2019·Clinical Linguistics & Phonetics·Vasiliki KoukouliotiPanagiotis Ioannidis
Mar 3, 2021·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Marianna PapadopoulouNikolaos Karandreas
Sep 3, 2021·Acta neurologica Belgica·Georgios PapadopoulosPanagiotis Ioannidis

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