Adaptation to a low carbohydrate high fat diet is rapid but impairs endurance exercise metabolism and performance despite enhanced glycogen availability.

The Journal of Physiology
Louise M BurkeAvish P Sharma

Abstract

Brief (5-6 days) adaptation to a low carbohydrate high fat diet in elite athletes increased exercise fat oxidation to rates previously observed with medium (3-4 weeks) or chronic (>12 months) adherence to this diet, with metabolic changes being washed out in a similar time frame. Increased fat utilisation during exercise was associated with a 5-8% increase in oxygen cost at speeds related to Olympic Programme races. Acute restoration of endogenous carbohydrate (CHO) availability (24 h high CHO diet, pre-race CHO) only partially restored substrate utilisation during a race warm-up. Fat oxidation continued to be elevated above baseline values although it was lower than achieved by 5-6 days' keto adaptation; CHO oxidation only reached 61% and 78% of values previously seen at exercise intensities related to race events. Acute restoration of CHO availability failed to overturn the impairment of high-intensity endurance performance previously associated with low carbohydrate high fat adaptation, potentially due to the blunted capacity for CHO oxidation. We investigated substrate utilisation during exercise after brief (5-6 days) adaptation to a ketogenic low-carbohydrate (CHO), high-fat (LCHF) diet and similar washout period. Thirtee...Continue Reading

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Citations

Dec 4, 2020·Nutrients·Alannah K A McKayPeter Peeling
Dec 11, 2020·Journal of the International Society of Sports Nutrition·Merry A BestardGeorge H Crocker
Oct 8, 2020·Medicine and Science in Sports and Exercise·Jamie WhitfieldAvish P Sharma
Feb 2, 2021·The Journal of Physiology·Scott K Powers, Michael C Hogan
May 19, 2021·Journal of the International Society of Sports Nutrition·Kasper Degn Gejl, Lars Nybo
May 12, 2021·Current Opinion in Clinical Nutrition and Metabolic Care·Javier T Gonzalez, Gareth A Wallis
Apr 13, 2021·American Journal of Physiology. Endocrinology and Metabolism·Tai-Yu HuangRobert C Noland
Jun 3, 2021·International Journal of Environmental Research and Public Health·Abdullah F AlghannamMaha H Alhussain
Jun 7, 2021·Journal of the International Society of Sports Nutrition·Julie L ColemanLee M Margolis
Sep 14, 2021·Sports Medicine·Caoileann H Murphy, Chris McGlory
Sep 18, 2021·Journal of the International Society of Sports Nutrition·A Antonio PaoliGiuseppe Marcolin

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Methods Mentioned

BETA
X‐ray
three hybrid
biopsies

Software Mentioned

GraphPad
G Power
GraphPad Prism

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