PMID: 11913655Mar 27, 2002Paper

Adaptive constraints and the phylogenetic comparative method: a computer simulation test

Evolution; International Journal of Organic Evolution
E l MartinsElizabeth A Housworth

Abstract

Recently, the utility of modern phylogenetic comparative methods (PCMs) has been questioned because of the seemingly restrictive assumptions required by these methods. Although most comparative analyses involve traits thought to be undergoing natural or sexual selection, most PCMs require an assumption that the traits be evolving by less directed random processes, such as Brownian motion (BM). In this study, we use computer simulation to generate data under more realistic evolutionary scenarios and consider the statistical abilities of a variety of PCMs to estimate correlation coefficients from these data. We found that correlations estimated without taking phylogeny into account were often quite poor and never substantially better than those produced by the other tested methods. In contrast, most PCMs performed quite well even when their assumptions were violated. Felsenstein's independent contrasts (FIC) method gave the best performance in many cases, even when weak constraints had been acting throughout phenotypic evolution. When strong constraints acted in opposition to variance-generating (i.e., BM) forces, however, FIC correlation coefficients were biased in the direction of those BM forces. In most cases, all other PCMs ...Continue Reading

References

Dec 21, 1989·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·A Grafen
Jun 29, 1995·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·A Purvis
Mar 1, 1997·Molecular Biology and Evolution·R BleiweissJ C Matheus
Apr 29, 1997·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·T Price
Jun 17, 2000·Trends in Ecology & Evolution·E l Martins
Jul 6, 2000·Science·J P HuelsenbeckJ P Masly
Dec 29, 2000·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·P H Harvey, A Rambaut

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Citations

Jan 24, 2004·Mathematical Biosciences·Colleen Kelly, Trevor D Price
Jun 5, 2008·Heredity·T R Gregory, J S Johnston
May 16, 2009·Nucleic Acids Research·Jorn BruggemanBernd W Brandt
Apr 22, 2006·Proceedings. Biological Sciences·Andrew E McKechnieWalter Jetz
Mar 30, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Graham N StoneJoseph Felsenstein
Jul 20, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Robert PoulinDavid W Thieltges
Feb 10, 2004·Applied and Environmental Microbiology·Scott R Miller, Brad M Bebout
Feb 24, 2009·Genome Génome / Conseil National De Recherches Canada·Chandler B Andrews, T Ryan Gregory
Oct 4, 2011·PLoS Pathogens·Ben LongdonFrancis M Jiggins
Apr 1, 2009·Genetics and Molecular Biology·José Alexandre Felizola Diniz-FilhoThiago Fernando L V B Rangel
Jan 1, 2009·Genetics and Molecular Biology·José Alexandre Felizola Diniz-Filho, João Carlos Nabout
Oct 12, 2012·Genetics and Molecular Biology·José Alexandre F Diniz-FilhoLuis Mauricio Bini
Nov 20, 2015·The New Phytologist·Chase M MasonLisa A Donovan
Mar 8, 2013·Journal of Human Evolution·Amy L BauernfeindChet C Sherwood
Sep 4, 2012·Journal of Theoretical Biology·Krzysztof BartoszekThomas F Hansen
Apr 7, 2010·Journal of Theoretical Biology·Thibaut JombartDominique Pontier
May 5, 2009·Journal of Theoretical Biology·Pierre Legendre, Yves Desdevises
Mar 11, 2008·Zoology : Analysis of Complex Systems, ZACS·Rachel Lockridge MuellerJeffrey L Boore
Oct 13, 2007·Journal of Human Evolution·Matthew C O'Neill, Seth D Dobson
Dec 17, 2014·Evolution; International Journal of Organic Evolution·Chad M EliasonMatthew D Shawkey
Feb 25, 2009·American Journal of Physical Anthropology·Seth D Dobson
May 20, 2004·Journal of Evolutionary Biology·S QuaderN E Seavy
Aug 12, 2008·Journal of Evolutionary Biology·R J Butler, A Goswami
Aug 20, 2008·American Journal of Physical Anthropology·Seth D Dobson
May 3, 2008·Evolution; International Journal of Organic Evolution·Thomas F HansenSteven Hecht Orzack
Jan 16, 2008·Journal of Evolutionary Biology·D W E HoneM J Benton
Aug 9, 2007·Evolution; International Journal of Organic Evolution·Alejandro Gonzalez-VoyerHugh Drummond
Jan 22, 2009·Evolution; International Journal of Organic Evolution·Liam J Revell, David C Collar
Jan 22, 2009·Evolution; International Journal of Organic Evolution·Brett A GoodmanLin Schwarzkopf
Dec 1, 2006·Evolution; International Journal of Organic Evolution·Lumir Gvozdík, Raoul Van Damme
Jan 30, 2013·Evolution; International Journal of Organic Evolution·Achaz von Hardenberg, Alejandro Gonzalez-Voyer
Feb 11, 2011·Journal of Evolutionary Biology·I GalvánJ Erritzøe
Nov 24, 2011·Journal of Evolutionary Biology·M LaurinJ Cubo
Apr 11, 2012·Evolution; International Journal of Organic Evolution·José Alexandre Felizola Diniz FilhoLuis Mauricio Bini
Mar 1, 2012·American Journal of Primatology·Seth D Dobson
May 4, 2011·Annals of the New York Academy of Sciences·Jeroen B SmaersKarl Zilles
Jul 5, 2012·Evolution; International Journal of Organic Evolution·Ian S Pearse, Andrew L Hipp

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