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ADAR1: "Editor-in-Chief" of Cytoplasmic Innate Immunity

Frontiers in Immunology

Jul 25, 2019

Mart M LamersBart L Haagmans

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Abstract

Specialized receptors that recognize molecular patterns such as double stranded RNA duplexes-indicative of viral replication-are potent triggers of the innate immune system. Although their activation is beneficial during viral infection, RNA transcribed from endogenous mobile genetic el...read more

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Adenosine Deaminase
Autoimmune Diseases
Immune Tolerance
Ligands
RNA
RNA, Double-Stranded
Virus Diseases
Virus Replication
EIF-2 Kinase
Patterns
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ADAR1: "Editor-in-Chief" of Cytoplasmic Innate Immunity

Frontiers in Immunology

Jul 25, 2019

Mart M LamersBart L Haagmans

PMID: 31404141

DOI: 10.3389/fimmu.2019.01763

Abstract

Specialized receptors that recognize molecular patterns such as double stranded RNA duplexes-indicative of viral replication-are potent triggers of the innate immune system. Although their activation is beneficial during viral infection, RNA transcribed from endogenous mobile genetic el...read more

Mentioned in this Paper

Adenosine Deaminase
Autoimmune Diseases
Immune Tolerance
Ligands
RNA
Paper Details
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