Addiction in developmental perspective: influence of conduct disorder severity, subtype, and attention-deficit hyperactivity disorder on problem severity and comorbidity in adults with opioid dependence

Journal of Addictive Diseases
Pieter-Jan CarpentierCornelis A J De Jong

Abstract

This retrospective cross-sectional study examines whether conduct disorder and attention deficit hyperactivity disorder are associated with problem severity and psychiatric comorbidity in 193 middle-aged, opioid-dependent patients. Conduct disorder history, attention deficit hyperactivity disorder, psychiatric comorbidity, and problem severity were assessed by structured interviews and validated instruments. A conduct disorder history was confirmed in 116 (60.1%) participants. Conduct disorder patients had significantly higher problem severity scores, more frequent comorbid substance use disorders, and more severe psychiatric comorbidity. Attention deficit hyperactivity disorder was found to increase the risk for psychiatric comorbidity. Conduct disorder persistence is a useful model for elucidating complex psychiatric comorbidity of opioid-dependent patients.

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Citations

Jan 30, 2015·Substance Abuse Treatment, Prevention, and Policy·Sari CastrénKaarlo Simojoki
Jul 31, 2012·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·P J CarpentierJ K Buitelaar
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Aug 23, 2016·Neuroscience and Biobehavioral Reviews·Nathalie E HolzDaniel Brandeis
Oct 4, 2016·Social Cognitive and Affective Neuroscience·Nathalie E HolzManfred Laucht
Mar 9, 2017·Harvard Review of Psychiatry·Pieter-Jan Carpentier, Frances R Levin
Oct 16, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nathalie E HolzManfred Laucht

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Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

SPSS
Statistical Package for the Social Sciences

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