Adding ancillary features to enhancement patterns of hepatocellular carcinoma on gadoxetic acid-enhanced magnetic resonance imaging improves diagnostic performance

Abdominal Radiology
Ji Hye MinMin-Ji Kim

Abstract

To assess the added value of intratumoral ancillary features to conventional enhancement pattern-based diagnosis of hepatocellular carcinoma (HCC) on gadoxetic acid-enhanced magnetic resonance imaging (MRI). A total of 773 consecutive patients with surgically resected 773 primary hepatic tumors (699 HCCs, 63 intrahepatic cholangiocarcinomas, and 11 benign nodules) who underwent gadoxetic acid-enhanced MRI were retrospectively identified. Enhancement patterns and three ancillary features of capsule, septum, and T2 spotty hyperintensity were assessed by two radiologists. Performance of enhancement pattern-based diagnosis of HCC was compared to diagnosis of HCC based on enhancement pattern plus ancillary features. Enhancement patterns were positive (arterial diffuse hyperenhancement with washout) for 562 (72.7%) tumors, negative (no arterial hyperenhancement and no washout) for 75 (9.7%), and inconclusive (either no arterial hyperenhancement or no washout) for 136 (17.6%). Capsule was observed in 498 (64.4%) tumors, septum in 521 (67.3%), and T2 spotty hyperintensity in 107 (13.8%). The accuracy and sensitivity of HCC diagnosis was improved significantly after adding at least one ancillary feature compared with enhancement pattern...Continue Reading

References

Jan 1, 1997·European Radiology·L Martí-Bonmatí
Jul 27, 2001·Virchows Archiv : an International Journal of Pathology·M IshizakiT Tsuji
Jun 15, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Luigi BolondiFabio Piscaglia
Dec 12, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Alejandro FornerJordi Bruix
Mar 5, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jordi BruixUNKNOWN American Association for the Study of Liver Diseases
Jun 28, 2011·AJR. American Journal of Roentgenology·Young Joo SuhKi Whang Kim
Mar 20, 2012·Journal of Hepatology·UNKNOWN European Association For The Study Of The Liver, UNKNOWN European Organisation For Research And Treatment Of Cancer
Aug 18, 2012·Magnetic Resonance Imaging·Naoki KanataKazuro Sugimura
Jan 1, 2010·Oncology Letters·Masaru FujimotoHirohisa Yano
Jul 22, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Donald G MitchellClaude B Sirlin
Apr 29, 2015·Gut and Liver·UNKNOWN Korean Liver Cancer Study Group (KLCSG), UNKNOWN National Cancer Center, Korea (NCC)
Mar 10, 2016·Journal of Computer Assisted Tomography·Eric M BlaschkeAytekin Oto
Apr 23, 2016·European Journal of Gastroenterology & Hepatology·Haizhen QianGuangwu Lin

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