Addition of dexmedetomidine or lornoxicam to prilocaine in intravenous regional anaesthesia for hand or forearm surgery: a randomized controlled study.

Clinical Drug Investigation
Iclal O KolCaner Mimaroglu

Abstract

Intravenous regional anaesthesia (IVRA) is a simple and cost-effective technique that is ideally suited for surgery involving the distal arm. This study compared the effect of lornoxicam or dexmedetomidine in IVRA with prilocaine in patients who underwent hand or forearm surgery. M ethods: This randomized, double-blind study enrolled 75 patients scheduled for hand or forearm surgery. IVRA was achieved with 2% prilocaine 3 mg/kg in the control group (n=25), 2% prilocaine 3 mg/kg plus dexmedetomidine 0.5 microg/kg in the dexmedetomidine group (n=25), and 2% prilocaine 3 mg/kg plus lornoxicam 8 mg in the lornoxicam group (n=25). In all groups, 0.9% NaCl solution was added to make up a total volume of 40 mL. Sensory and motor block onset and recovery times, haemodynamic variables, visual analogue scale (VAS) pain and sedation scores, duration of analgesia, total analgesic consumption over 24 hours, adverse effects and quality of anaesthesia were recorded. Sensory block onset was shorter and sensory block recovery time longer in the dexmedetomidine group compared with the lornoxicam and control groups (p<0.05). Sensory and motor block recovery times and duration of analgesia for tourniquet were prolonged in the dexmedetomidine and l...Continue Reading

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Citations

Dec 12, 2012·Journal of Anaesthesiology, Clinical Pharmacology·Alok KumarBarun Datta
Oct 26, 2013·Revista española de anestesiología y reanimación·P G AtanassoffJ L Aguilar
Jan 16, 2016·Brazilian Journal of Anesthesiology·Hande ÇelikNermin Göğüş
Dec 10, 2015·Revista brasileira de anestesiologia·Hande ÇelikNermin Göğüş
Nov 16, 2010·Anesthesiology Clinics·Usha RamadhyaniBobby D Nossaman
Dec 24, 2015·Journal of Anesthesia·Medha MohtaNavneet Kaur
Jan 13, 2016·Indian Journal of Anaesthesia·Shalini Pravin SardesaiAdnanali Sarkar
Nov 19, 2014·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·H S Abdel-GhaffarM M Roushdy
May 30, 2013·Expert Opinion on Pharmacotherapy·Christian Hillstrom, Jan G Jakobsson
Jun 1, 2012·Current Therapeutic Research, Clinical and Experimental·Kenan KaygusuzCaner Mimaroglu
Dec 23, 2009·American Journal of Therapeutics·Joy AlleeJoseph D Tobias

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