PMID: 8583767Sep 1, 1995Paper

Additive benefits of EFAs in dogs with atopic dermatitis after partial response to antihistamine therapy

The Journal of Small Animal Practice
S Paterson

Abstract

It has been reported that 20 to 70 per cent of atopic cases in the dog can be controlled with antihistamines, though the effective antihistamine cannot be predetermined. Combination therapy with essential fatty acids (EFAs) and antihistamines has been shown to be useful in dogs. All of the work published to date has been performed in open studies, without the use of placebo, and in dogs where the aim has been to control pruritus as a symptom rather than that caused specifically by atopy. The aim of this study was to assess the combined effects of four antihistamines; hydroxyzine, chlorpheniramine, cyproheptadine and clemastine; with both an EFA supplement and a placebo of olive oil, in 25 dogs to control pruritus in clinically proven cses of atopy.

References

Dec 1, 1991·The British Journal of Dermatology·S Wright
Nov 1, 1990·The Veterinary Clinics of North America. Small Animal Practice·D E Bevier
Sep 1, 1988·The Veterinary Clinics of North America. Small Animal Practice·E J Rosser
Feb 1, 1982·The Veterinary Clinics of North America. Small Animal Practice·D W Scott

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Citations

Sep 13, 2001·Veterinary Immunology and Immunopathology·D J DeBoer, C E Griffin
Sep 13, 2001·Veterinary Immunology and Immunopathology·T OlivryA Hillier
Sep 7, 1999·The Journal of Small Animal Practice·D W Scott, W H Miller
Sep 3, 2002·Research in Veterinary Science·B K SaevikO Taugbøl
Jun 23, 2004·The Journal of Small Animal Practice·R S MuellerT L Greenwalt
Jun 7, 2003·Veterinary Dermatology·T OlivryUNKNOWN International Task Force on Canine Atopic Dermatitis
Sep 24, 2010·Journal of Veterinary Pharmacology and Therapeutics·S K SinghR K Jadhav
Mar 2, 2010·Veterinary Dermatology·Thierry OlivryHywel C Williams
Apr 20, 2007·British Journal of Clinical Pharmacology·Hakan CinemreAdem Gungor

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Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.