Additive effect of dorzolamide hydrochloride to patients taking travoprost: a retrospective study

Optometry : Journal of the American Optometric Association
Stephen Boyer, Dax Gay

Abstract

A retrospective chart review study at a Veterans Affairs hospital evaluated intraocular pressure change after dorzolamide hydrochloride 2% was administered to patients already using travoprost. A literature search found no other study that looked specifically at this combination of drugs. A chart review of 46 patients at the Veterans Affairs Illiana Health Care System was performed evaluating the intraocular pressures after dorzolamide hydrochloride was added to travoprost. Baseline intraocular pressures were obtained on patients who had been on travoprost at least 4 months. Endpoint intraocular pressures were then obtained from the visit closest to 6 months after the addition of dorzolamide hydrochloride. An average intraocular pressure reduction of an additional 20.6% was observed after adding only dorzolamide hydrochloride to travoprost. This study confirmed our clinical observations that dorzolamide hydrochloride added to travoprost is an excellent and safe choice to further lower intraocular pressures.

References

Oct 8, 1999·American Journal of Ophthalmology·C J Ingram, R F Brubaker
Mar 16, 2002·The Annals of Pharmacotherapy·Christy L AlexanderSteven R Abel
Apr 4, 2002·Clinical Pharmacokinetics·Jens Martens-Lobenhoffer, Peter Banditt
May 31, 2002·American Journal of Ophthalmology·Daniel J O'ConnorAlden Mead
Feb 21, 2006·The British Journal of Ophthalmology·H A Quigley, A T Broman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Related Papers

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
Steven H McKinleySilvia Orengo-Nania
Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
Sumru OnalAhmet Gucukoglu
© 2022 Meta ULC. All rights reserved