Adenocarcinoma of the pancreas: a statistical analysis of biliary bypass vs Whipple resection in good risk patients.

Annals of Surgery
T M Shapiro

Abstract

A series of 297 patients with adenocarcinoma of the head of the pancreas was reviewed. Forty-eight patients was identified with disease limited to the pancreas or adjacent tissues. Twenty-four patients underwent Whipple resection. A second group of 24 patients underwent elective biliary bypass. No patient had liver, omental or peritoneal metastases. All cases of ampullary carcinoma and islet cell tumors were excluded. Assessment of clinical and laboratory parameters revealed the two groups to be statistically comparable. There were no 5-year survivors in either groups. Mean duration of survival was not significantly different. Life table analysis showed no significant difference between the survival rates of the two groups. Frequency of clinic followup, rehospitalization and reexploration were used to assess palliation. Success of palliation was poor in both groups and no statistically significant differences were noted. Surgical mortality in the resected group was 8% and did not differ from the 4% surgical mortality in the bypass group. Surgical morbidity was significantly higher in the resected group. Implications of this data in the management of patients with resectable carcinoma of the pancreas are discussed.

Citations

Aug 1, 1984·Journal of Surgical Oncology·I R Gough, G Mumme
Oct 1, 1983·Journal of Clinical Pathology·I JeffreyB W Ellis
Aug 1, 1997·Postgraduate Medical Journal·D Ravichandran, C D Johnson
Dec 18, 2001·Journal of Clinical Gastroenterology·George H Sakorafas, Adelais G Tsiotou
Aug 10, 2002·Annals of Surgery·Markus SchäferPierre-Alain Clavien
Jun 12, 2009·Journal of Hepato-biliary-pancreatic Sciences·Zhongxue SuJunji Yamamoto
Aug 18, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Saboor KhanMichael B Farnell
Sep 16, 2010·ANZ Journal of Surgery·Kelvin H K KwokDouglas Fenton-Lee
Aug 25, 2020·Pancreas·Thilo HackertMarkus W Büchler
Mar 1, 1985·Journal of Surgical Oncology·J M RosenbergW P Macaulay
Mar 1, 1985·Journal of the Royal Society of Medicine·M A Al-Fallouji, R E Collins
Oct 1, 1982·The British Journal of Surgery·H ObertopH Van Houten
Feb 1, 1987·The British Journal of Surgery·M Trede
Dec 1, 1984·World Journal of Surgery·M G Sarr, J L Cameron
Oct 1, 1983·The British Journal of Surgery·I A Eyre-BrookA G Johnson
Oct 1, 1989·The Australian and New Zealand Journal of Surgery·R C Smith
Nov 3, 1998·Alimentary Pharmacology & Therapeutics·A HaycoxT Walley
Dec 1, 1984·World Journal of Surgery·F Kümmerle, K Rückert
Sep 26, 2002·World Journal of Surgery·Peter WamserReinhold Fuegger
Jun 24, 2005·ANZ Journal of Surgery·Parul J ShuklaLuis J Desouza
Mar 23, 2007·AJR. American Journal of Roentgenology·Manabu HashimotoYuzo Yamamoto
Apr 4, 2007·The American Journal of Gastroenterology·Yasser ShaibHashem El-Serag
Aug 2, 2007·Journal of Clinical Gastroenterology·George H SakorafasGeorge Peros
Sep 4, 2010·Case Reports in Medicine·Walid FarajMohamed Khalife
Dec 1, 2009·The Indian Journal of Surgery·H Ramesh
Jun 3, 2010·World Journal of Surgery·Paleswan Joshi LakheyMahesh Khakurel
Nov 17, 2016·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·Birgir Gudjonsson
Oct 1, 1980·The Australian and New Zealand Journal of Surgery·H Ross, R A Jonas
Dec 1, 1995·Scandinavian Journal of Gastroenterology·G J Ridder, J Klempnauer
Dec 1, 1979·The Journal of Pathology·D A Levison
Jul 1, 1991·Scandinavian Journal of Gastroenterology·D O ArnarS Kjartansson
May 1, 1990·Gut·D C Carter
Mar 1, 1984·The British Journal of Surgery·C P ArmstrongG C Davies
Mar 15, 1980·British Medical Journal·D C Carter
Jun 27, 2003·Journal of Surgical Oncology·Cosimo SpertiSergio Pedrazzoli

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