Adenoid cystic carcinoma of the larynx: a report of six cases with review of the literature

Acta Oto-laryngologica
Wei Liu, Xiaohong Chen

Abstract

Adenoid cystic carcinoma (ACC) in the larynx is an extremely rare entity. Although the 5-year disease-specific survival rates for laryngeal ACC are high, distant metastasis might occur up to more than 5 years post treatment. Therefore patients with ACC require long-term follow-up. To summarize the characteristics of laryngeal ACC by analyzing six cases in a single center. This was a retrospective analysis of six patients with laryngeal ACC who were treated in Beijing Tongren Hospital between 1998 and 2013. The mean age at diagnosis was 44 years, ranging from 15 to 61 years. Dyspnea was the most common complaint. All patients underwent combined-modality treatment with surgical resection and external beam radiation. The range of follow-up time varied from 1 to 7 years (median 5 years). Follow-up inspections indicated that none of them had local or regional recurrence. Distant metastasis occurred in 33.7% (2/6) of the patients, with one lung metastasis 5 years after operation and one liver metastasis 4 years after operation.

References

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Citations

Jan 25, 2016·Auris, Nasus, Larynx·Takashi KashiwagiShin-Ichi Haruna
Nov 12, 2016·Nigerian Medical Journal : Journal of the Nigeria Medical Association·Ayotunde James FasunlaOnyekwere George Nwaorgu
Dec 25, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Emily MarchianoJean Anderson Eloy
Jun 29, 2018·Vestnik otorinolaringologii·L G KozhanovA Yu Kostin
Feb 23, 2017·Advances in Therapy·Fernando LópezAlfio Ferlito
Nov 26, 2019·The Pan African Medical Journal·Asmaa NaimMustapha Essaadi
Dec 22, 2019·Medicine·Yu CuiZhanpeng Zhu
Mar 3, 2021·American Journal of Otolaryngology·Marco LionelloAndy Bertolin
Jul 16, 2021·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Giulio Cantù
Aug 6, 2021·Laryngo- rhino- otologie·Stephan HackenbergAgmal Scherzad

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