Adenolipoma of the thyroid gland: report of a case

Surgery Today
Wataru KitagawaKunihiko Ito

Abstract

We report a case of adenolipoma of the thyroid gland, which is very unusual because thyroid adenoma rarely contains mature adipose tissue. A 55-year-old Japanese woman presented with a 1-month history of a neck mass. A blinded fine-needle aspiration biopsy showed benign follicular cells with no adipose cells, and we performed a left hemithyroidectomy. The specimen measured 7.0 x 4.4 cm and weighed 59.9 g. The cut surface of the tumor revealed a solid yellowish mass, and hematoxylin-eosin staining showed that the solid tumor was well separated from the adjacent thyroid tissue by a thin fibrous capsule. The tumor was found to be follicular adenoma composed of epithelial cells arranged in monotonous microfollicular patterns, intermingled with mature adipose tissue. No adipose tissue was found outside the tumor, and there were no signs of amyloid deposits in the tumor or adjacent thyroid tissue. The pathological diagnosis was adenolipoma of the thyroid gland. We discuss the pathogenesis of this entity and review the previously documented cases.

Citations

Apr 16, 2010·Journal of Postgraduate Medicine·P V PradeepB A Ramakrishna
Nov 18, 2009·Annals of Diagnostic Pathology·Yimin GeAlberto G Ayala
Mar 21, 2006·Annals of Diagnostic Pathology·Keyla Pineda DaboinMario A Luna
Sep 10, 2014·BMJ Case Reports·Nicholas FitzpatrickRichard Lewis
Jan 28, 2018·Journal of Ultrasound·Monica PennisiGiuliana Costanzo
Jan 26, 2021·Annales de pathologie·Sirine AyadiIlhem Charfeddine

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