PMID: 7248908Aug 1, 1981Paper

Adenomas of the small intestine: a clinicopathologic review of 51 cases and a study of their relationship to carcinoma

K H Perzin, M F Bridge


The authors studied 51 patients who had small bowel tumors that contained adenomatous epithelium. These rare lesions were identified among 392,000 surgical pathology cases seen during a 62-year period. Grossly and histologically, adenomas arising in the mucosa of the small intestine are similar to the adenomas found in the colon. Of the 51 patients, 18 had adenomas, and 33 had tumors that contained both adenoma and carcinoma in the same lesion, including five intramucosal and 28 invasive carcinomas. The location of the tumor usually determined which clinical problems were produced. The data indicate that adenomas originating in the small bowel mucosa probably are premalignant lesions and that many primary adenocarcinomas of the small intestine arise in adenomas. Of the authors' 130 apparently primary small bowel carcinomas (including the papilla of Vater), 33 (25%) histologically demonstrated adenomatous epithelium in the same lesion. Factors associated with an increased chance of finding carcinoma in an adenoma include adenoma type, size of lesion, location, and multicentricity. Carcinomas appear to develop more frequently in papillary (villous) adenomas than in ordinary adenomas. The larger the lesion is, the more likely carc...Continue Reading


Jun 22, 1979·JAMA : the Journal of the American Medical Association·B M Gold
May 1, 1978·Diseases of the Colon and Rectum·A A Keshgegian, H T Enterline
May 13, 1976·The New England Journal of Medicine·R W Erbe
Jul 1, 1976·American Journal of Surgery·M F SchultenJ M Beal
Nov 1, 1976·American Journal of Surgery·K OhmoriK Satake
Feb 1, 1975·Annals of Surgery·N D KutinS A Localio
Apr 1, 1975·The American Journal of Digestive Diseases·V A LiVolsi, K H Perzin
Sep 1, 1974·Oral Surgery, Oral Medicine, and Oral Pathology·A Kjaerkeim, T Stokke
Sep 1, 1971·The American Journal of Digestive Diseases·A CohenW Lawrence
Jun 1, 1973·The American Journal of Digestive Diseases·S H Mir-MadjlessiW A Hawk
Mar 12, 1973·JAMA : the Journal of the American Medical Association·P L SchnurE G Harrison
May 1, 1974·Archives of Surgery·J E Ross, J E Mara
Jul 1, 1972·Radiology·E J RingJ L Clements
Sep 1, 1972·American Journal of Surgery·Y DayalH Goldman
Jul 1, 1972·Gut·R N Melmed, I A Bouchier
Sep 1, 1971·Khirurgiia·V I Borodianskiĭ, N G Rabinovich
Mar 1, 1966·American Journal of Surgery·W OstermillerL Weibel
Jun 1, 1970·The American Journal of Digestive Diseases·R D ColiW R Thayer
Apr 1, 1970·Gut·T G ParksH E Lockhart-Mummery
Feb 1, 1971·The British Journal of Surgery·D C Hoffmann, J C Goligher
Apr 1, 1968·The Journal of Pediatrics·B R DuncanJ H Priest
Sep 1, 1968·Archives of Surgery·W O GriffenL R Bryant
Jun 1, 1968·The American Journal of Digestive Diseases·A J Martel, C A Bonanno
Oct 1, 1969·Archives of Surgery·R H YonemotoR B Rosen
Sep 1, 1966·Radiology·A D MeltzerH J Isard
Mar 1, 1967·American Journal of Surgery·J M MacdonaldA D Berk
May 1, 1953·The British Journal of Surgery·W R HUNTER, W A WILSON
May 1, 1954·American Journal of Surgery·I N INGRAM, W C DAVIS
Sep 1, 1954·American Journal of Surgery·W S ELIASR YONEMOTO
Nov 10, 1955·The New England Journal of Medicine·R S WEINER, P COOPER
Dec 1, 1956·Annals of Internal Medicine·J D CARBALLO, R C GUMPEL
Feb 26, 1959·The New England Journal of Medicine·R C DARLING, C E WELCH
Jul 1, 1959·A.M.A. Archives of Surgery·J A ROCK, E R FISHER
Jan 1, 1960·American Journal of Surgery·E M ALRICHJ J FOMON
Dec 1, 1961·American Journal of Surgery·M C ANDERSON, W H GREGOR
Jan 11, 1962·The New England Journal of Medicine·R B CATTELLF KAHN
Oct 20, 1962·JAMA : the Journal of the American Medical Association·V A MCKUSICK
Apr 1, 1963·Archives of Internal Medicine·J L ACHORD, H D PROCTOR

❮ Previous
Next ❯


Oct 1, 1990·Journal of Surgical Oncology·H MatsuuraY Haraguchi
Jan 1, 1992·Journal of Surgical Oncology·F SerourM Krispin
Sep 1, 1989·Digestive Diseases and Sciences·F ParafJ C Chaput
Dec 1, 1985·World Journal of Surgery·M J Cooper, R C Williamson
Jan 1, 1987·Gastrointestinal Radiology·M DavisA K Haque
Sep 1, 1986·The Japanese Journal of Surgery·Y UchidaS Yokoyama
Sep 1, 1988·Diseases of the Colon and Rectum·R L NelsonH Abcarian
May 1, 1994·Indian Journal of Pediatrics·K N RattanT S Jaswal
Apr 22, 2003·Pathology Oncology Research : POR·Gábor ElekAkos Pap
Jul 1, 2008·Abdominal Imaging·S GusminiA Del Maschio
Jun 8, 2002·World Journal of Surgery·Claus-Dieter HeideckeJörg-Rüdiger Siewert
Apr 11, 2009·Surgical Endoscopy·Min Kyu JungYong Hwan Choi
May 22, 2010·Surgical Endoscopy·Jong Won SohnIn Kwon Chung
Jan 29, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Luciana Bertocco de Paiva HaddadJosé Jukemura
Mar 1, 1997·American Journal of Surgery·M VeyrièresM Julien
Mar 5, 2004·Gastrointestinal Endoscopy·Kenji TsuchidaMakoto Itoh
Aug 28, 2004·Gastrointestinal Endoscopy·Darius ApelJürgen Ferdinand Riemann
Nov 24, 2004·Gastrointestinal Endoscopy·Chi-Liang ChengGlen A Lehman
Jul 19, 2001·The Surgical Clinics of North America·J M SarmientoM B Farnell
Jul 31, 2013·Nature Reviews. Clinical Oncology·Kanwal Raghav, Michael J Overman
Jul 20, 2000·The Australian and New Zealand Journal of Surgery·M D HuttonP Imani
May 1, 1989·Annals of Surgery·C W ChappuisI Cohn
Nov 1, 1996·Annals of Surgery·G D BranumW C Meyers
Jun 1, 1997·Journal of Clinical Gastroenterology·A KapurR Vasudeva
Apr 21, 2007·Pancreas·Akira HayashibeShinichiro Makimoto
Aug 2, 2008·The American Journal of Surgical Pathology·Patrick L WagnerRhonda K Yantiss
Oct 13, 2012·Annals of Surgery·Eugene P CeppaTheodore N Pappas
Feb 24, 2007·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·John A BatsisAmindra S Arora
Jan 1, 1996·International Journal of Urology : Official Journal of the Japanese Urological Association·N TsuboniwaT Kotake
Nov 1, 1990·The Australian and New Zealand Journal of Surgery·P R EvansL A Easton
Jul 17, 2003·Gut·S D RampertabP H R Green
Sep 1, 1986·Journal of Clinical Pathology·T NakamuraG Nakano
Jul 1, 1990·Journal of Clinical Pathology·T F Lioe, J D Biggart
May 1, 1994·Journal of Clinical Pathology·N M VargheseA Theodossi
Jul 1, 1996·Journal of Clinical Pathology·D J MacGowanC O'Morain
Dec 22, 2011·Annals of Surgical Oncology·Michael J OvermanGeorge J Chang
Jun 27, 2014·Journal of Medical Case Reports·Konstantinos AlexiouNikolaos Economou
Apr 1, 1996·Scandinavian Journal of Gastroenterology·M Stolte, C Pscherer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Barrett Esophagus

Barrett’s esophagus if a serious complication of gastroesophageal reflux disease during which the normal esophageal lining changes to tissue that resembles intestinal lining. Here is the latest research.