Adenomatous ductal proliferation/hyperplasia in the parotid gland associated without any other pathological lesions; a report and survey of the literatures

Medical Molecular Morphology
Bhoj Raj AdhikariYoshihiro Abiko

Abstract

Adenomatous ductal proliferation/hyperplasia (ADP/H) is a rare hyperplastic condition of the salivary gland. It is mostly associated with other salivary gland pathologies such as tumors and inflammations, and is incidentally found in tissue sections during histopathological examinations of those diseases. Herein, we report a case of ADP/H in the parotid gland not associated with any other pathological lesions, and present a review of the literature on this condition. A 60-year-old Japanese female complained of swelling on the left side of parotid region. Clinical examination revealed a swelling on the lower lobe of the left parotid gland. The lesion was firm but non-tender and was not attached to adjacent structures. A clinical diagnosis of benign salivary gland tumor was reached, and surgical excision was performed under general anesthesia. Histopathological examination revealed an intact parotid gland capsule with isomorphic and basaloid cells within scanty cytoplasm. In addition, an admixture of hyperplasia and proliferation of the intercalated ducts, the presence of zymogen granules, the absence of solid nests, and a peripheral palisaded arrangement of the cells were observed. Based on these findings, a diagnosis of ADP/H w...Continue Reading

References

Feb 15, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·G Y Yu, K Donath
Jun 20, 2002·Advances in Anatomic Pathology·Mario A Luna
Jun 2, 2007·Histopathology·W Cheuk, J K C Chan
Jun 23, 2009·The American Journal of Surgical Pathology·Ilan WeinrebBayardo Perez-Ordoñez
Jan 25, 2012·Head and Neck Pathology·Matthew R NaunheimDerrick T Lin
Mar 31, 2012·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Jacinthe ChênevertRaja R Seethala
Dec 17, 2014·Human Pathology·Elizabeth A BilodeauRaja R Seethala
Sep 8, 2017·Case Reports in Oncology·Nobuhiko SekiTetsuo Himi

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