PMID: 8590597Jul 1, 1995Paper

Adenosine dialdehyde blocks the disappearance of two nerve growth factor-induced insoluble proteins

Journal of Protein Chemistry
J Y VanDenburg, P N McFadden

Abstract

Two nonionic-detergent-insoluble proteins are induced early in the nerve growth factor (NGF)-induced neuronal differentiation of PC12 cells. The pools of these two proteins then disappear from the insoluble fraction after a few days of continued exposure of the cells to NGF. The methylation-inhibiting drug adenosine dialdehyde blocks the disappearance of these insoluble proteins, implicating a methylation-dependent step in the pathway that regulates the fate of these proteins.

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Citations

Oct 4, 2012·Animal : an International Journal of Animal Bioscience·D P MorgaviG T Attwood

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