Adenosine-triphosphate-binding cassette transporter-1 trafficking and function

Trends in Cardiovascular Medicine
Martin H KangM R Hayden

Abstract

Mutations in the adenosine-triphosphate-binding cassette transporter-1 (ABCA1) lead to Tangier disease, a genetic disorder characterized by an almost complete absence of plasma high-density lipoprotein cholesterol. Although the importance of ABCA1 localization to its cholesterol efflux function has been extensively characterized, the cellular itinerary of ABCA1 leading to the plasma membrane is not fully elucidated. This review will summarize the current knowledge of ABCA1 trafficking and its relationship to function. Understanding these crucial processes provides potential novel therapeutic targets to regulate high-density lipoprotein biogenesis through influencing pathways of ABCA1 trafficking.

References

Sep 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·Y Takahashi, J D Smith
Jan 21, 2001·The Journal of Biological Chemistry·O ChambenoitG Chimini
May 12, 2001·The Journal of Biological Chemistry·E B NeufeldH B Brewer
May 18, 2001·Biochemical and Biophysical Research Communications·A R TanakaK Ueda
Mar 16, 2002·Laboratory Investigation; a Journal of Technical Methods and Pathology·Cheryl L WellingtonMichael R Hayden
Aug 15, 2002·Biochemical and Biophysical Research Communications·Tohru OhamaYuji Matsuzawa
Jan 4, 2003·The Journal of Clinical Investigation·Nan WangAlan R Tall
Jan 28, 2003·The Journal of Biological Chemistry·Robert S KissYves L Marcel
May 22, 2003·Progress in Biophysics and Molecular Biology·Catherine van VlietPaul A Gleeson
Jul 19, 2003·The Journal of Biological Chemistry·Laurent O MartinezAlan R Tall
Jan 15, 2004·The Journal of Biological Chemistry·Youichi MunehiraKazumitsu Ueda
Jan 20, 2004·The Journal of Biological Chemistry·Ying FuDmitri Sviridov
Apr 21, 2005·The Journal of Clinical Investigation·Jenelle M TimminsJohn S Parks
May 24, 2005·Biochemical and Biophysical Research Communications·Wei-Ting ChaoVivian C Yang
Oct 20, 2005·Cellular and Molecular Life Sciences : CMLS·J-R Nofer, A T Remaley
May 20, 2006·The Journal of Biological Chemistry·Doriane TrompierGiovanna Chimini
Jun 27, 2006·Biochimica Et Biophysica Acta·Clara CavelierArnold von Eckardstein
Oct 20, 2006·Molecular Biology of the Cell·Matts D LinderElina Ikonen
Nov 14, 2006·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Nadia AmeenNeil A Bradbury
May 5, 2007·Arteriosclerosis, Thrombosis, and Vascular Biology·Charulatha VedhachalamMichael C Phillips
Jun 20, 2007·European Biophysics Journal : EBJ·Stéphane OrlowskiXavier Collet
Jul 28, 2007·Biochemistry·Nigora MukhamedovaDmitri Sviridov
Oct 2, 2007·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Iris LorenziLucia Rohrer
Mar 18, 2008·Biochemical and Biophysical Research Communications·Arowu R TanakaMasayuki Murata
Oct 29, 2008·Journal of Lipid Research·Linda J Pike
Dec 30, 2008·Advanced Drug Delivery Reviews·Kanako Wakabayashi-NakaoToshihisa Ishikawa
Feb 10, 2009·Current Topics in Medicinal Chemistry·Letizia PorcelliAmalia Azzariti
Feb 24, 2009·Nature Reviews. Molecular Cell Biology·Douglas C ReesOded Lewinson

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Citations

Dec 25, 2013·Biochimica Et Biophysica Acta·Magdolna SzántóPéter Bai
May 28, 2013·DNA and Cell Biology·Yun-cheng LvChao-ke Tang
Jul 27, 2011·Biochimica Et Biophysica Acta·Tomasz BocerGiovanna Chimini
Apr 14, 2012·The International Journal of Biochemistry & Cell Biology·Gabriela CastilhoMarisa Passarelli
Jun 10, 2015·Critical Reviews in Food Science and Nutrition·Fatemeh Ramezani KapourchaliMohammed H Moghadasian
Sep 11, 2012·Molecular Genetics and Metabolism·Tommaso FasanoSebastiano Calandra
Jul 19, 2011·Atherosclerosis·Rachel J SuetaniSally P A McCormick
Nov 2, 2013·Journal of Lipid Research·Clemens RöhrlHerbert Stangl
Oct 19, 2013·Arteriosclerosis, Thrombosis, and Vascular Biology·Martin H KangMichael R Hayden
Jan 11, 2019·American Journal of Physiology. Gastrointestinal and Liver Physiology·Jessica P OtisSteven A Farber
Jan 15, 2019·Current Opinion in Lipidology·Emile LevySchohraya Spahis
Aug 1, 2013·Physiological Reviews·Paul N Hopkins
Nov 5, 2013·Virulence·Birju A Shah, James F Padbury
Jul 31, 2014·The Journal of Biological Chemistry·Michael C Phillips
May 16, 2020·Critical Reviews in Biochemistry and Molecular Biology·Hye-Won Shin, Hiroyuki Takatsu
Jul 20, 2012·Physiological Reviews·Nada A Abumrad, Nicholas O Davidson
Apr 22, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Deepak SharmaPradeep Sharma
Jun 5, 2021·Clinical Science·Diana Cardoso, Esperanza Perucha
Oct 7, 2017·Arteriosclerosis, Thrombosis, and Vascular Biology·Alain Théophile SanéEmile Levy
Jul 27, 2021·Frontiers in Cell and Developmental Biology·Lucas A TavaresLuis L P daSilva

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