Adenosquamous carcinoma of the pancreas: a single-institution experience comparing resection and palliative care

Journal of the American College of Surgeons
Rory L SmootFlorencia G Que

Abstract

Adenosquamous carcinoma is a rare malignancy of the exocrine pancreas. Previous literature has reported dismal survival for these patients. We examined our single-institution experience with this tumor to compare survival for sugical resection and palliative therapy. Records were reviewed for patients with adenosquamous pancreatic cancer evaluated during the years 1985 to 2003. Pathology specimens were reviewed. Survival was calculated by Kaplan-Meier method and categorical variables were compared with Chi-square analysis. A p value < 0.05 was considered significant. Twenty-three patients were identified with adenosquamous carcinoma of the pancreas. Twelve patients underwent curative resection and 11 patients had either no surgery or a palliative bypass procedure. For the resection group the mean age was 69 years (7 men). In the nonoperative group the mean age was 65 years (6 men). Operative procedures included standard pancreaticoduodenectomy (PD), 4 patients; pyloruspreserving PD, 3 patients; and distal pancreatectomy, 5 patients. Median length of stay was 13.5 days (7-30 d). Morbidity included delayed gastric emptying (4 patients), leak (2 patients), superficial skin infection, abscess, and GI bleed (1 patient each). There w...Continue Reading

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Citations

Jul 10, 2010·Langenbeck's Archives of Surgery·Paolo RegiClaudio Bassi
Nov 18, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Matthew Harold G KatzJason A Zell
Aug 11, 2010·Southern Medical Journal·Guru Trikudanathan, Constantin A Dasanu
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Nov 28, 2012·Journal of Digestive Diseases·Hiroyuki MatsubayashiHiroyuki Ono
Dec 5, 2014·World Journal of Gastroenterology : WJG·Bao-Chun LuJian-Hui Yang
Nov 17, 2020·The Journal of Surgical Research·Maitham A MoslimSanjay S Reddy
Feb 25, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Joerg KaiserOliver Strobel

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