PMID: 5919452Nov 11, 1966

Adenovirus multiplication: inhibition by methisazone

Science
D J BAUER, K Apostolov

Abstract

Methisazone (5 to 40 microM) inhibited the multiplication of types 3, 7, 9, 11, 14, 16, 17, 21, and 28 adenovirus; SV15 (a simian adenovirus) was also inhibited. A study of adenovirus 11 under single-cycle conditions showed that multiplication of the virus, was completely inhibited by 30 microM methisazone when addition of the compound was delayed until 13 hours after infection. A survey showed that the structure-activity relations of the action of methisazone against adenoviruses and pox viruses are similar.

Citations

Jan 1, 1980·Pharmacology & Therapeutics·B Loddo
Jan 1, 1981·Pharmacology & Therapeutics·D D Perrin, H Stünzi
Jan 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·W LevinsonJ M Bishop
Mar 4, 1977·Annals of the New York Academy of Sciences·E C Herrmann, J A Herrmann
Mar 1, 1967·Postgraduate Medical Journal·H A Reimann
Mar 2, 2011·Bioorganic & Medicinal Chemistry Letters·Iou-Jiun KangJyh-Haur Chern
Dec 29, 2015·Bioorganic & Medicinal Chemistry·Gökçe Cihan-ÜstündağGültaze Çapan
Dec 1, 1971·The American Journal of Medicine·S Z Hirschman
Nov 1, 1979·Current Problems in Pediatrics·J W St Geme
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Apr 26, 2018·Mini Reviews in Medicinal Chemistry·Paulo André Teixeira De Moraes GomesAna C Lima Leite

Related Concepts

Adenoviruses
Antibody Formation
Antiviral Agents
HeLa Cells
Idoxuridine, Radical Ion (1-)
Poxviridae
Thiosemicarbazones
Culture Techniques

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