Adequacy of cervical sampling in hysterectomy specimens for endometrial cancer

Annals of Diagnostic Pathology
Sheeba SyedDavid Millan

Abstract

To determine whether sampling one section, which includes the anterior and posterior cervical lips in hysterectomy specimens, provides the best prospect for detecting stromal invasion in hysterectomy specimens for endometrial cancers. To assess the most likely section in which cervical stromal invasion was identified in 29 cases. Cervical stromal invasion was detected in first section in 75.8% cases, whereas 24.1% detected in random sections other than first section. Cervical stromal invasion is most likely to be identified in one section taken in the midline, which includes anterior and posterior lips. However, in a significant number of cases, this one section missed invasion, which was detected in other random cervical sections. Therefore, sampling of one block (anterior and posterior) from the cervix is insufficient for detecting cervical stromal invasion for endometrial cancer.

References

Jun 11, 1992·Gynecologic Oncology·S C RubinJ L Lewis
Aug 1, 1989·British Journal of Obstetrics and Gynaecology·J H Shepherd
Apr 4, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J J JobsenL N Ten Cate
Feb 28, 2002·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·L B Jordan, A Al-Nafussi
Jan 26, 2011·The American Journal of Surgical Pathology·W Glenn McCluggageRichard J Zaino
Jun 20, 2015·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·W Glenn McCluggageUNKNOWN International Collaboration on Cancer Reporting

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Citations

Dec 15, 2018·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Anais MalpicaEsther Oliva
Jul 25, 2019·American Journal of Clinical Pathology·Bronwyn H BryantAlexandra N Kalof
Feb 14, 2019·Der Pathologe·L-C HornUNKNOWN Kommission zur Erstellung der S3-Leitlinie „Diagnostik, Therapie und Nachsorge der Patientinnen mit Endometriumkarzinom“

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