Adherence issues related to sublingual immunotherapy as perceived by allergists.

Patient Preference and Adherence
S ScuratiItalian Study Group on SLIT Compliance

Abstract

Sublingual immunotherapy (SLIT) is a viable alternative to subcutaneous immunotherapy to treat allergic rhinitis and asthma, and is widely used in clinical practice in many European countries. The clinical efficacy of SLIT has been established in a number of clinical trials and meta-analyses. However, because SLIT is self-administered by patients without medical supervision, the degree of patient adherence with treatment is still a concern. The objective of this study was to evaluate the perception by allergists of issues related to SLIT adherence. We performed a questionnaire-based survey of 296 Italian allergists, based on the adherence issues known from previous studies. The perception of importance of each item was assessed by a VAS scale ranging from 0 to 10. Patient perception of clinical efficacy was considered the most important factor (ranked 1 by 54% of allergists), followed by the possibility of reimbursement (ranked 1 by 34%), and by the absence of side effects (ranked 1 by 21%). Patient education, regular follow-up, and ease of use of SLIT were ranked first by less than 20% of allergists. These findings indicate that clinical efficacy, cost, and side effects are perceived as the major issues influencing patient adh...Continue Reading

References

Feb 13, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·V Di RienzoG Passalacqua
Oct 14, 2004·The Journal of Allergy and Clinical Immunology·Elio NovembreAlberto Vierucci
May 19, 2005·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G B GidaroG Ciprandi
Aug 5, 2005·The New England Journal of Medicine·Lars Osterberg, Terrence Blaschke
Dec 13, 2005·The Journal of Allergy and Clinical Immunology·Giovanni Battista PajnoGiovanni Barberio
Feb 14, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Giovanni PassalacquaGianenrico Senna
Aug 8, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Cevdet OzdemirIsil B Barlan
Nov 7, 2008·Current Opinion in Allergy and Clinical Immunology·Patrizia BertoCristoforo Incorvaia
Feb 12, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Enrico CompalatiGiorgio Walter Canonica
Apr 17, 2009·The Journal of Allergy and Clinical Immunology·Philippe-Jean BousquetJean Bousquet
Jan 1, 2008·Patient Preference and Adherence·Cristoforo IncorvaiaFranco Frati

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Citations

Dec 22, 2011·Clinical Reviews in Allergy & Immunology·Christopher Chang
Apr 4, 2013·Current Opinion in Otolaryngology & Head and Neck Surgery·William R Reisacher, Jiovani M Visaya
Mar 13, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Linda S CoxRichard Lockey
Jan 3, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G PassalacquaG W Canonica
Jul 1, 2014·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A Antico
Apr 13, 2015·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Carlo Lombardi

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