Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia

The Pan African Medical Journal
Moses MukoshaBellington Vwalika

Abstract

regular use of Antiretroviral Therapy (ART) in pregnancy and breastfeeding reduces the odds of Mother-to-Child HIV Transmission (MTCT). However, adherence to ART is critical for MTCT to be successful. The present study investigated factors that influence adherence to ART among HIV infected pregnant women in Zambia. a cross-sectional study design was conducted involving 71 HIV infected pregnant women who were advised to join the Prevention of Mother-to-Child HIV Transmission (PMTCT) program during their routine Antenatal clinic (ANC) visit and were on ART for more than six months. We used the Medication Possession Ratio (MPR) to quantify adherence levels. We used logistic regression to establish factors that influence adherence to ART. a total of 71 HIV infected pregnant women with a median age of 27years (IQR, 25-30) were enrolled in the study. There was evidence of a difference in adherence levels between pregnant women above 30 years and ones between 15 years and 30 years (P<0.001). Median adherence levels in this group were found to be at 96%(IQR 89-97). The main predictor of adherence in this population was marital status (being on separation) and age. The women who were on separation were 0.14 times less likely to adhere t...Continue Reading

References

Jan 6, 2005·The Journal of Infectious Diseases·P Richard HarriganJulio S G Montaner
Jan 29, 2014·AIDS·Lyson TenthaniUNKNOWN Ministry of Health in Malawi and IeDEA Southern Africa
Dec 2, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Mary Pat KiefferUNKNOWN EGPAF Technical Directors Forum
Feb 20, 2016·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Ellen C CanigliaUNKNOWN Center for AIDS Research Network of Integrated Clinical Systems and the HIV-CAUSAL Collaboration
Mar 24, 2016·Antimicrobial Agents and Chemotherapy·Fred KyeyuneMiguel E Quiñones-Mateu
Aug 10, 2016·Journal of Viral Hepatitis·N AllardB Cowie
Feb 2, 2017·The New England Journal of Medicine·David C KnoxDarrell H S Tan
Mar 14, 2017·International Journal of Environmental Research and Public Health·Dinberu SeyoumNiko Speybroeck
Jun 28, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G RocheleauP R Harrigan
Aug 7, 2017·Journal of the International AIDS Society·Happy MpawaJoep J van Oosterhout
Oct 27, 2017·The Lancet Infectious Diseases·Nathan FordGottfried Hirnschall
Jan 13, 2018·MMWR. Morbidity and Mortality Weekly Report·Kristin BrownAndrew C Voetsch
Apr 15, 2018·BMC Infectious Diseases·Oladele Vincent AdeniyiJohn Lambert
Nov 16, 2018·AIDS Research and Human Retroviruses·Benjamin ChimukangaraTulio de Oliveira
Jan 25, 2019·Expert Opinion on Pharmacotherapy·Amedeo Capetti, Giuliano Rizzardini
Mar 2, 2019·BMC Pregnancy and Childbirth·Dawit Jember TesfayeFanuel Belayneh Bekele

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