Adherence to Bisphosphonates among People Admitted to an Orthopaedic and Geriatric Ward at a University Hospital in Sweden

Pharmacy : Journal of Pharmacy, Education and Practice
Linnea Abramsson, Maria Gustafsson

Abstract

Oral bisphosphonates are the first choice of therapy to reduce the risk of osteoporotic fractures. These medications have generally poor oral bioavailability, which may further be reduced by concomitant intake of certain foods and drugs; therefore, it is vital to follow specific instructions. The aim with this study was to assess general adherence to oral bisphosphonates and adherence to specific administration instructions among people admitted to two wards at Umeå University hospital in Sweden. This interview study focuses on elderly patients living at home and prescribed oral bisphosphonates. Invited were 27 patients admitted to an orthopaedic ward and a geriatric ward during the period 28 March 2017 and 5 December 2017. In total, 21 patients were interviewed regarding their adherence to oral bisphosphonates. Out of 21 patients, 13 (62%) were considered non-adherent. The most common reason was calcium intake less than 2 h after oral administration of bisphosphonate (54%). The number of regularly prescribed drugs was significantly higher among patients rated non-adherent to bisphosphonates compared to those rated adherent (p =0.004). Adherence to bisphosphonates administration instruction among elderly people living at home w...Continue Reading

References

Apr 9, 2005·Drugs & Aging·Eric J MacLaughlinChester A Bond
Apr 6, 2006·The Annals of Pharmacotherapy·Cynthia L RaehlRebecca B Sleeper
Apr 3, 2009·Journal of Aging and Health·Tamara L HayesJeffrey A Kaye
Jul 21, 2009·International Journal of Cardiology·Helen SmithCharles George
Jun 10, 2010·Korean Diabetes Journal·Kyung-Ae ParkSung-Taek Hyun
Feb 3, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E LandfeldtF Borgström
Apr 5, 2011·The American Journal of Geriatric Pharmacotherapy·Walid F GelladZachary A Marcum
Apr 17, 2012·Clinics in Geriatric Medicine·Zachary A Marcum, Walid F Gellad
Aug 14, 2012·Journal of Clinical Nursing·Maria A HenriquesJosé Cabrita
May 1, 2010·Therapeutic Advances in Chronic Disease·E Michael Lewiecki
Mar 5, 2013·Geriatrics & Gerontology International·Vivian W Y LeeDiana Tze Fan Lee
Oct 1, 2009·Pharmacy Practice·Lotte S Haugbølle, Hanne Herborg
Sep 20, 2017·Archives of Gerontology and Geriatrics·Jenny HallgrenAnna K Dahl Aslan
Oct 24, 2017·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Umberto TarantinoMaria Luisa Brandi

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Citations

Feb 2, 2020·Journal of Orthopaedic Surgery and Research·Hasan R MohammadDavid W Murray

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