Adherence to oral second-generation antipsychotic medications in patients with schizophrenia and bipolar disorder: physicians' perceptions of adherence vs. pharmacy claims.

International Journal of Clinical Practice
J J StephensonR Dirani

Abstract

To compare physician-reported adherence of specific patients to oral second-generation antipsychotics vs. actual adherence rates determined from the patients' pharmacy claims. Claims data from the HealthCore Integrated Research Database identified patients with schizophrenia or bipolar disorder with ≥ 1 oral second-generation antipsychotic prescription. The prescribing physicians were identified from the pharmacy claims and asked to complete an Internet survey assessing their perception of medication adherence for 1-2 of their patients and their beliefs regarding adherence to second-generation antipsychotics in general for a 1-year period. Adherence to second-generation antipsychotics was determined for each patient by pharmacy claims for the same period. Physician survey data were merged with patient claims data via unique patient identifiers, and physician-reported adherence rates were compared with claims-based rates as measured by the medication possession ratio. One hundred and fifty-three physicians responded to the survey, representing 214 patients (44 with claims for schizophrenia, 162 with bipolar disorder, 8 with claims for bipolar disorder and schizophrenia). Most physicians (60%) had no formal adherence training. Mo...Continue Reading

References

Jan 1, 1995·Schizophrenia Bulletin·P J Weiden, M Olfson
Jan 1, 1997·Schizophrenia Bulletin·W S FentonR K Heinssen
Feb 19, 1998·Schizophrenia Research·J L Ayuso-Gutiérrez, J M del Río Vega
May 9, 1998·Psychiatric Services : a Journal of the American Psychiatric Association·J A Cramer, R Rosenheck
Feb 2, 2000·Psychiatric Services : a Journal of the American Psychiatric Association·M OlfsonP J Weiden
Jan 5, 2002·The American Journal of Psychiatry·Christian R DolderDilip V Jeste
Mar 21, 2002·Journal of General Internal Medicine·Loren G MillerNeil S Wenger
Nov 30, 2002·Medical Care·Joel M SchectmanJohn D Voss
Nov 11, 2003·Current Medical Research and Opinion·Ibrahim S Al-ZakwaniTara R Cockerham
May 3, 2006·The Journal of Clinical Psychiatry·Haya Ascher-SvanumJeff W Swanson
May 16, 2006·Bipolar Disorders·Martha SajatovicRosalinda V Ignacio
May 19, 2006·Schizophrenia Bulletin·Dawn I VelliganAlexander L Miller
Nov 10, 2006·The Journal of Dermatological Treatment·Monali J BhosleRajesh Balkrishnan
May 31, 2007·Psychiatric Services : a Journal of the American Psychiatric Association·Matthew J ByerlyA John Rush
Sep 4, 2007·Psychiatric Services : a Journal of the American Psychiatric Association·Dawn I VelliganAlexander L Miller
Jan 19, 2008·Clinical Therapeutics·Mark VanelliAmy Troxell-Dorgan
Mar 4, 2008·The Journal of Clinical Psychiatry·Michael R LawAlyce S Adams
May 6, 2008·The Journal of Clinical Hypertension·Donald E MoriskyHarry J Ward
Jan 1, 2008·Patient Preference and Adherence·Michael Birnbaum, Zafar Sharif
Jan 16, 2010·Journal of Clinical Psychopharmacology·Clifford M CassidyAshok Malla
Feb 2, 2010·Journal of the National Cancer Institute·Rajeshwari SridharaRichard Pazdur
Aug 3, 2010·Psychiatric Services : a Journal of the American Psychiatric Association·Elizabeth KhaykinGail L Daumit
Jun 1, 2003·Primary Care Respiratory Journal : Journal of the General Practice Airways Group·Eric van GanseElisabeth Ståhl

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Citations

Sep 25, 2012·Current Psychiatry Reports·Amy M KilbourneChristopher J Miller
Jul 1, 1978·Clinica Chimica Acta; International Journal of Clinical Chemistry·J Potter, P J Nestel
Jul 16, 2016·Journal of Child and Adolescent Psychopharmacology·Tina R GoldsteinBoris Birmaher
Oct 6, 2018·Current Medical Research and Opinion·Daisy Ng-Mak, Krithika Rajagopalan
Aug 18, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Cozumel S PruetteKristin A Riekert
Sep 5, 2019·International Journal of Bipolar Disorders·M BauerP C Whybrow
Jul 25, 2013·Current Opinion in Psychiatry·Sarah C E Chapman, Rob Horne
May 2, 2018·International Journal of Bipolar Disorders·Maximilian PilhatschMichael Bauer
May 5, 2018·Advances in Therapy·Joanna P MacEwanFelicia M Forma
Aug 13, 2021·Population Health Management·Alexandria SkoufalosDexter Waters

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