PMID: 8981092Dec 1, 1996Paper

Adhesion of Helicobacter pylori strains to alpha-2,3-linked sialic acids

Glycoconjugate Journal
S HirmoT Wadström

Abstract

Helicobacter pylori is a human pathogen associated with gastritis and peptic ulcer. Adhesion properties of H. pylori to various structures have been described in the literature, including evidence for sialic acid-binding. To study the specificity and frequency of sialic acid-binding, fourteen H. pylori strains were investigated using haemagglutination with derivatized erythrocytes carrying sialic acids only on defined glycans and using haemagglutination inhibition assays. From these studies H. pylori strains can be grouped into sialic acid-dependent and sialic acid-independent classes. The sialic acid-dependent strains require alpha-2,3-linked sialic acid for haemagglutination. The potential roles of sialic acid-dependent adhesions for H. pylori-related infections are discussed.

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Citations

May 10, 2008·Glycoconjugate Journal·Louise RoyleStephen D Carrington
Aug 13, 1999·Journal of Microbiological Methods·S HirmoB Nilsson
Dec 25, 2008·Glycobiology·Halina Miller-PodrazaKarl-Anders Karlsson
Apr 22, 2003·Infection and Immunity·Sean O HynesTorkel Wadström
Feb 24, 2004·Infection and Immunity·Niamh RocheSusann Teneberg
Aug 2, 2011·BMC Biochemistry·Hendrik Koliwer-BrandlSørge Kelm
Feb 17, 2001·Helicobacter·D J Evans, D G Evans
Jan 20, 1999·Alimentary Pharmacology & Therapeutics·A R OpekunD Y Graham
Feb 6, 2010·Medicinal Research Reviews·Ashish A KulkarniSuri S Iyer
Mar 19, 2014·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Serhan Sakarya, Necati Gunay
May 4, 2005·FEMS Immunology and Medical Microbiology·Hayley J Bennett, Ian S Roberts
Feb 1, 1997·FEMS Immunology and Medical Microbiology·S HirmoR Schauer
Oct 23, 1997·Clinical Microbiology Reviews·B E DunnM J Blaser
Oct 26, 2002·International Journal of Medical Microbiology : IJMM·Stefan OdenbreitRainer Haas

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