Adjustable inspiratory occlusion valve in experimental bronchopleural fistula. A new therapeutic perspective

Acta Cirúrgica Brasileira
Maria Gabriela Cavicchia TonelotoAntonio Luis Eiras Falcão

Abstract

To assess the efficacy of an adjustable inspiratory occlusion valve in experimental bronchopleural fistula during mechanical ventilation. We studied six mechanically ventilated pigs in a surgically created, reproducible model of bronchopleural fistula managed with mechanical ventilation and water-sealed thoracic drainage. An adjustable inspiratory occlusion valve was placed between the thoracic drain and the endotracheal tube. Hemodynamic data, capnography and blood gases were recorded before and after the creation of the bronchopleural fistula as well as after every adjustment of the inspiratory occlusion valve. When compared with the standard water-sealed drainage treatment, the use of an adjustable inspiratory occlusion valve improved the alveolar tidal volume and reduced bronchopleural air leak (p<0.001), without hemodynamic compromise when compared with conventional water sealed drainage. The use of an adjustable inspiratory occlusion valve improved the alveolar tidal volume, reduced alveolar leak, in an experimental reproducible model of bronchopleural fistula, without causing any hemodynamic derangements when compared with conventional water sealed drainage.

References

Feb 1, 1989·The Journal of Surgical Research·F G SpinaleH D Reines
Oct 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·E G Chaddouk
Jul 1, 1996·Australian Veterinary Journal·C R BellengerM R Pearson
Sep 28, 2000·Journal of Applied Physiology·J G WoodN C Gonzalez
Aug 10, 2005·Seminars in Respiratory and Critical Care Medicine·R R Kempainen, D J Pierson
Jun 17, 2006·Chest·Francesco LeoLorenzo Spaggiari
Sep 19, 2006·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J H T FerreiraM M Moreira
Jul 14, 2009·Journal of Critical Care·Kiran ShekarMorgan Windsor
Jun 10, 2010·Vascular Health and Risk Management·Marcos Mello MoreiraOtavio Rizzi Coelho
Nov 17, 2011·Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular·Daniel José PereiraHeitor Moreno Junior
Dec 2, 2011·Journal of Cardiothoracic and Vascular Anesthesia·Camila Ferreira LeiteRicardo Kalaf Mussi
Jan 24, 2012·Interactive Cardiovascular and Thoracic Surgery·Claudio AndreettiErino A Rendina
Sep 8, 2012·Journal of Intensive Care Medicine·Adrian A Maung, Lewis J Kaplan
Dec 28, 2012·Jornal de pediatria·Maria Ângela G O RibeiroIlma A Paschoal
Jan 30, 2015·Acta Cirúrgica Brasileira·Douglas Guimaraes de OliveiraAntonio Luis Eiras Falcão

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