Adjuvant chemotherapy in resected lung cancer: two-year experience in a university hospital.

Canadian Respiratory Journal : Journal of the Canadian Thoracic Society
Nichole BouchardYves Lacasse

Abstract

Randomized trials have confirmed the benefits of adjuvant chemotherapy in improving survival in resected early-stage non-small-cell lung cancer (NSCLC). The extent to which these results have translated into clinical practice is unknown. To examine the referral pattern of patients with resected lung cancer to adjuvant chemotherapy, and to compare compliance and toxicities with current literature. A retrospective analysis of all patients who underwent a surgical resection for lung cancer at Laval Hospital (Quebec City, Quebec) from March 2004 to January 2006 was conducted. A total of 258 patients underwent surgery. Seven patients were excluded because of early postoperative death, and two patients were excluded because of incomplete data. Data from 249 patients were analyzed (94% NSCLC). Fifty per cent were referred to medical oncology for consideration of adjuvant chemotherapy, including 37 of 61 patients with stage II NSCLC. One hundred patients received chemotherapy. No significant difference in age, sex, comorbidities and surgical procedures was observed between those who received chemotherapy and those who did not. Chemotherapy was initiated 47 days (median) after the surgery and consisted mainly of cisplatin-vinorelbine (3...Continue Reading

Citations

Mar 2, 2012·Journal of Oncology Practice·Tawee TanvetyanonPaul B Jacobsen
Apr 25, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sinead CuffeFrances A Shepherd
Jan 1, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Bala Basak Oven UstaaliogluMahmut Gumus
Jun 11, 2016·Annals of Surgical Oncology·Eleftherios MamounasVincent Antao
Oct 27, 2012·Implementation Science : IS·Robin UrquhartGeoffrey A Porter

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