Adjuvant therapy efficacy of Chinese drugs pharmaceutics for COPD patients with respiratory failure: a meta-analysis

Bioscience Reports
Chunqiu LiuXuejing Wang

Abstract

We performed a meta-analysis to evaluate the efficacy and safety of Western medicine combined with Tanreqing for patients with chronic obstructive pulmonary disease (COPD) and respiratory failure. We comprehensively searched several online databases from the times of their inception to November 2018. The trial quality was assessed using the bias risk tool recommended by the Cochrane library. Relative risks (RRs) and their 95% confidence intervals (CIs) for binary outcomes and weighted mean differences (MDs) with 95% CIs for continuous data were calculated. A fixed effect model indicated that integrated Tanreqing group experienced higher overall treatment effectiveness (RR = 1.23, 95% CI: 1.17-1.30, P=0.000). Pooled results from random effects models indicated the oxygen partial pressure of the test group was significantly higher than that of the control groups (MD = 9.55, 95% CI: 4.57-14.52, P<0.000). The carbon dioxide pressure of the test group was significantly lower than that of the control groups (MD = -6.06, 95% CI: -8.19 to -3.93, P=0.000). The lung function score of the test group was significantly higher than that of the control group (MD = 7.87, 95% CI: 4.45-11.29). Sensitivity analysis indicated that the data were st...Continue Reading

References

Sep 1, 1986·Controlled Clinical Trials·R DerSimonian, N Laird
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
May 6, 2008·Proceedings of the American Thoracic Society·Neil MacIntyre, Yuh Chin Huang
Jul 2, 2008·Respiratory Medicine·Taixiang WuPhillippa Poole
Feb 23, 2010·International Journal of Surgery·David MoherUNKNOWN PRISMA Group
Nov 26, 2010·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Yunqing ZhongJuanjuan Fu
Sep 20, 2011·Biopharmaceutics & Drug Disposition·Chenrui LiZhong Zuo
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Sep 17, 2013·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Wei ZhouLiuqing Di
Feb 20, 2014·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Ian G StiellGeorge A Wells
Jul 10, 2017·Mayo Clinic Proceedings·Shireen Mirza, Roberto Benzo
Oct 6, 2017·International Journal of Chronic Obstructive Pulmonary Disease·Rafael GolpeElena Arellano-Orden
Oct 28, 2017·The European Respiratory Journal·Catherine E CharronDave Singh

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