Adjuvant Tirofiban Injection Through Deployed Solitaire Stent As a Rescue Technique After failed Mechanical Thrombectomy in Acute Stroke

Neurointervention
Jung Hwa SeoEun-Gyu Kim

Abstract

We present our experiences of intra-arterial tirofiban injection through a deployed Solitaire stent as a rescue therapy after failed mechanical thrombectomy in patients with acute ischemic stroke. Data on 18 patients treated with adjunctive tirofiban injection through a temporarily deployed Solitaire stent after failed mechanical thrombectomy were retrospectively reviewed. Solitaire stent was used as a primary thrombectomy device in 16 of 18 patients. Two patients received manual aspiration thrombectomy initially. If initial mechanical thrombectomy failed, tirofiban was injected intra-arterially through the deployed Solitaire stent and then subsequent Solitaire thrombectomy was performed. Fourteen patients had occlusions in the middle cerebral artery, 2 in the distal internal carotid artery, and 2 in the basilar artery. Successful recanalization was achieved in 14 patients (77.7%) after intra-arterial injection of tirofiban and subsequent Solitaire thrombectomy. Three patients without successful recanalization after rescue method received angioplasty with stenting. Overall, successful recanalization (TICI grades 2b and 3) was achieved in 17 (94.4%) of 18 patients. Periprocedural complications occurred in 5 patients: distal migr...Continue Reading

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Citations

Jun 9, 2017·Journal of Stroke·Byung Moon Kim
Sep 3, 2017·Stroke; a Journal of Cerebral Circulation·Jang-Hyun BaekOh Young Bang
Sep 9, 2018·Journal of Neurointerventional Surgery·Kubilay AydinSergin Akpek
Feb 13, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M YangZ Miao
Sep 16, 2017·Experimental and Therapeutic Medicine·Hongchen ZhaoTianming Shi
May 22, 2019·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Ying LuoJinglun Li
May 22, 2019·Stroke; a Journal of Cerebral Circulation·Andrew M DemchukUNKNOWN STAIR X (Stroke Treatment Academic Industry Roundtable) writing contributors
Sep 11, 2020·Oxidative Medicine and Cellular Longevity·Maciej BladowskiAdrian Doroszko

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