Administering RiaSTAP for Congenital Afibrinogenemia During Liver Transplant.

Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation
Chris GiordanoElizabeth Thomas

Abstract

Liver transplant has occasionally been performed in the presence of congenital afibrinogenemia and has been rarely used to treat it. Historically, to safely manage coagulopathy during transplant, these patients have been administered a combination of fresh frozen plasma and cryoprecipitate. In this case report, we discuss the first reported use of recombinant fibrinogen to treat such a patient and the decision-making process considered to balance the thrombotic and hemorrhagic risks.

References

Apr 26, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Ralph J FuchsWilliam Merritt
Jul 15, 2011·The New England Journal of Medicine·Armando Tripodi, Pier Mannuccio Mannucci
Aug 22, 2015·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Rubens Costa-FilhoDonat R Spahn
Dec 30, 2015·Journal of Thrombosis and Thrombolysis·Amihai RottenstreichYosef Kalish
Jun 14, 2016·Haemophilia : the Official Journal of the World Federation of Hemophilia·A Casini, P de Moerloose

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