Administration of a Polyphenol-Enriched Feed to Farmed Sea Bass (Dicentrarchus labrax L.) Modulates Intestinal and Spleen Immune Responses

Oxidative Medicine and Cellular Longevity
Thea MagroneLetizia Passantino

Abstract

Farmed fish are exposed to a continuous antigenic pressure by microbial and environmental agents, which may lead to a condition of chronic inflammation. In view of the notion that polyphenols, largely contained in fruits and vegetables, are endowed with antioxidant and anti-inflammatory activities, farmed sea bass (Dicentrarchus labrax L.) have been administered with red grape polyphenol-enriched feed. Polyphenols were extracted from the seeds of Canosina Nero di Troia Vitis vinifera and mixed with conventional feed at two different concentrations (100 and 200 mg/kg, resp.). Fish samples collected at days 223 and 273, respectively, were evaluated for intestinal and spleen cytokine release as well as for spleen macrophage (MØ) and melanomacrophage center (MMC) areas and distribution. Data will show that in treated fish decrease of intestinal interleukin- (IL-) 1β and IL-6 and increase of splenic interferon- (IFN-) γ occur. On the other hand, in the spleen reduction of MØ number seems to parallel increase in MMCs. Collectively, these data suggest that polyphenol-administered sea bass generate lower levels of intestinal proinflammatory cytokines, while producing larger amounts of spleen IFN-γ, as an expression of a robust and prot...Continue Reading

References

Jun 1, 1991·Immunology Today·G Beck, G S Habicht
Feb 1, 1985·The Journal of protozoology·J H Landsberg
May 1, 1974·European Journal of Immunology·A E Ellis, M De Sousa
Oct 25, 2003·Journal of Fish Diseases·C Agius, R J Roberts
Mar 17, 2004·Free Radical Biology & Medicine·Robert J WilliamsCatherine Rice-Evans
Jun 9, 2005·Fish & Shellfish Immunology·Børre Robertsen
Oct 19, 2006·Molecular Immunology·Dimitar B IlievFrederick W Goetz
Mar 6, 2008·Cellular & Molecular Immunology·Chien-Fu HuangChi-Chiang Yang
Jun 20, 2008·Fish & Shellfish Immunology·Timothy J Bowden
Jan 14, 2009·Journal of Structural Biology·José Dias CorrêaMarcos Farina
Jun 27, 2009·Fish & Shellfish Immunology·S M Sharifuzzaman, B Austin
Jun 5, 2010·The Proceedings of the Nutrition Society·Thea Magrone, Emilio Jirillo
Aug 7, 2010·Proceedings of the Japan Academy. Series B, Physical and Biological Sciences·Toshio Hirano
Oct 1, 2010·Journal of Anatomy·Erling O KoppangIvar Hordvik
Oct 25, 2011·Developmental and Comparative Immunology·Aina-Cathrine OvergårdSonal Patel
May 25, 2013·Current Pharmaceutical Design·Giuseppe MarzulliEmilio Jirillo
Aug 7, 2013·Immunity & Ageing : I & a·Thea Magrone, Emilio Jirillo
Jun 27, 2014·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sanjita Banerjee, Maria Leptin

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Citations

Mar 8, 2018·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Takwa BedhiafiEzzedine Aouani
Jan 5, 2019·Current Pharmaceutical Design·Thea MagroneEmilio Jirillo
Oct 12, 2018·Endocrine, Metabolic & Immune Disorders Drug Targets·Thea MagroneLetizia Passantino
Jul 2, 2020·Foods·Nayely Leyva-LópezErika Y Sánchez-Gutiérrez
Jul 28, 2020·Animals : an Open Access Journal From MDPI·Antonio CarminatoDaniela Bertotto
Dec 16, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Houcem SammariHichem Sebai

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Methods Mentioned

BETA
ELISA

Software Mentioned

GraphPad Prism
QWin

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