Admission calcium levels and risk of acute kidney injury in hospitalised patients

International Journal of Clinical Practice
Charat ThongprayoonStephen B Erickson

Abstract

The risk of acute kidney injury (AKI) development among hospitalised patients with elevated calcium levels on admission remains unclear. The aim of this study was to assess the risk of AKI in hospitalised patients stratified by various admission serum calcium levels. This is a single-centre retrospective study conducted at a tertiary referral hospital. All hospitalised adult patients who had admission calcium levels available between 2009 and 2013 were enrolled. Admission calcium was categorised based on its distribution into six groups (≤7.9, 8.0-8.4, 8.5-8.9, 9.0-9.4, 9.5-9.9, and ≥10.0 mg/dL). The primary outcome was hospital-acquired AKI. Logistic regression analysis was performed to obtain the odds ratio of AKI for various admission calcium strata using calcium levels of 8.0-8.4 mg/dL (lowest incidence of AKI) as the reference group. A total of 12 784 patients were studied. Hospital-acquired AKI occurred in 1779 (13.9%) patients. The incidence of AKI among patients with admission calcium ≤7.9, 8.0-8.4, 8.5-8.9, 9.0-9.4, 9.5-9.9 and ≥10 mg/dL was 14.7%, 11.7%, 11.8%, 14.6%, 15.8% and 17.3%, respectively. After adjusting for potential confounders, admission calcium levels ≤7.9, 9.0-9.4, 9.5-9.9 and ≥10 mg/dL were associated ...Continue Reading

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Citations

Jun 1, 2018·Hospital Practice·Wisit CheungpasitpornStephen B Erickson
Apr 17, 2020·Journal of Clinical Medicine·Charat ThongprayoonWisit Cheungpasitporn
Apr 17, 2020·Journal of Clinical Medicine·Charat ThongprayoonWisit Cheungpasitporn
Jul 10, 2019·Journal of Clinical Medicine·Charat ThongprayoonKianoush Kashani
May 10, 2020·Journal of the American Society of Nephrology : JASN·Ibrahim SandokjiF Perry Wilson
Jul 25, 2020·Scientific Reports·Charat ThongprayoonKianoush B Kashani
Aug 11, 2020·Advanced Biomedical Research·Wisit CheungpasitpornStephen B Erickson
Mar 7, 2020·Medicina·Charat ThongprayoonStephen B Erickson
Sep 30, 2020·International Journal of Clinical Practice·Charat ThongprayoonWisit Cheungpasitporn

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