Abstract
Stroke is one of the important causes of long-term disability-related deaths worldwide. Incidence and prevalence of stroke have been steadily increasing in India. Increasing interest has been focused on the role of admission hyperglycemia in the evolution of acute ischemic stroke. Very few studies were conducted in south India; hence, we intended to do this study. A total of 198 patients with acute ischemic stroke were included in a hospital-based longitudinal study to identify the independent factors (demographic, clinical, and biochemical parameters) associated with poor outcome (functional impairment-mRS ≥ 3 and mortality at 90 days of follow-up. Nearly, 75% of the patients presented with moderate-to-severe stroke. Out of the 198 patients, 117 (59%) had severe disability at admission. At 90 days of follow-up, it was observed that only 10 (5.5%) had severe disability. Patients with hyperglycemia exhibited greater functional impairment, that is, 96 out of 111 study subjects had modified Rankin score (mRS) ≥3, than those with normoglycemia (P < 0.0001). Mortality was high in hyperglycemics when compared with normoglycemics, that is, out of the 20 deaths, 13 patients had hyperglycemia and seven had normoglycemia at presentation ...Continue Reading
References
Oct 1, 1976·Journal of the Neurological Sciences·E Melamed
Apr 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·L KiersS Ratnaike
Jul 1, 1991·Stroke; a Journal of Cerebral Circulation·P A O'NeillD Bennett
Nov 1, 1990·Archives of Neurology·J WooM G Nicholls
Feb 1, 1988·Stroke; a Journal of Cerebral Circulation·E WooC Y Huang
Jul 1, 1985·Archives of Neurology·L CandeliseE Boccardi
Oct 1, 1994·Stroke; a Journal of Cerebral Circulation·H JørgensenT S Olsen
Aug 1, 1993·Stroke; a Journal of Cerebral Circulation·F van KootenP J Koudstaal
May 1, 1993·Journal of the Neurological Sciences·K MurrosA L Vuorela
Oct 6, 2001·Stroke; a Journal of Cerebral Circulation·S E CapesH C Gerstein
Mar 8, 2003·Stroke; a Journal of Cerebral Circulation·Salah-Eddine MegherbiUNKNOWN European BIOMED Study of Stroke Care Group
Aug 2, 2003·Stroke; a Journal of Cerebral Circulation·Tracey A BairdStephen M Davis
Feb 6, 2004·Stroke; a Journal of Cerebral Circulation·Perttu J Lindsberg, Risto O Roine
Jan 29, 2005·Diabetes Care·Brett M KisselaJoseph P Broderick
Jan 24, 2007·Lancet Neurology·Kathleen StrongRuth Bonita
Mar 22, 2008·Neurocritical Care·Latha G SteadRobert D Brown
Feb 13, 2009·Stroke; a Journal of Cerebral Circulation·Peter AppelrosAndreas Terént
Feb 21, 2009·Stroke; a Journal of Cerebral Circulation·Sapna E SridharanKurupath Radhakrishnan
Jul 16, 2009·Age and Ageing·Nikolaos KostulasVasilios Kostulas
Jul 9, 2010·Lancet·UNKNOWN Emerging Risk Factors CollaborationJ Danesh
Citations
Jun 12, 2020·Nigerian Journal of Clinical Practice·U Ozturk, O Ozturk
Oct 23, 2019·Biological Research for Nursing·Wan-Ling ChangYu-Ju Chen
Oct 18, 2019·Frontiers in Neurology·Bihong ZhuZhimin Wang
Dec 4, 2020·Neural Regeneration Research·Zhe ChengYu-Chuan Ding