Adolescence and the trajectory of alcohol use: introduction to part VI

Annals of the New York Academy of Sciences
Linda P Spear

Abstract

Research in the area of adolescent alcohol use is progressing rapidly, as exemplified by the chapters in this section. Basic animal research in rodents has revealed adolescents to be more sensitive than adults to ethanol-induced disruptions in brain plasticity, although adolescents conversely are relatively insensitive to ethanol cues that serve to moderate intake. Risks for excessive alcohol consumption due to genetic background have been shown in primate research to be exacerbated by adverse early life experiences. Studies in clinical populations have revealed neurocognitive deficits evident years following adolescent alcohol abuse, along with evidence that some neural changes may predate adolescent alcohol abuse, whereas others appear to be a consequence of this abuse. Further research is needed to detail determinants and consequences of adolescent alcohol abuse and to identify potential protective factors to diminish the propensity for excessive use of alcohol during this critical developmental period.

References

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Aug 2, 2002·Pharmacology, Biochemistry, and Behavior·Aaron M WhiteH Scott Swartzwelder
Jul 23, 2003·Pharmacology, Biochemistry, and Behavior·Tamara L DoremusLinda Patia Spear
Jul 15, 2004·Annals of the New York Academy of Sciences·Aaron M White, H Scott Swartzwelder
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Jul 15, 2004·Annals of the New York Academy of Sciences·Sandra A Brown, Susan F Tapert

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Citations

Dec 29, 2010·Alcohol·Ricardo Marcos PautassiNorman E Spear
Jan 22, 2008·Pharmacology, Biochemistry, and Behavior·David A WhiteStephen G Holtzman
Jun 30, 2009·Psychophysiology·Greg PerlmanWilliam G Iacono
Jan 9, 2007·Alcoholism, Clinical and Experimental Research·Deborah A DawsonTing-Kai Li
Mar 15, 2011·Developmental Psychobiology·Ricardo Marcos PautassiNorman E Spear
Apr 9, 2010·Alcoholism, Clinical and Experimental Research·Ricardo M PautassiYedy Israel
Feb 7, 2012·Drug and Alcohol Dependence·Justin J AnkerMarilyn E Carroll
Jan 10, 2012·Physiology & Behavior·Carmel M McDermottLaura A Schrader
Aug 9, 2016·Neuropsychologia·Aaron GoldsteinSuzanna Becker
Aug 10, 2011·Pharmacology, Biochemistry, and Behavior·Richard L BellWilliam J McBride
Mar 22, 2012·Alcoholism, Clinical and Experimental Research·Chiming HuangRosa Huang

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