ADP-ribosylation of serum proteins: elevated levels in neoplastic cases due to altered NAD/ADP-ribose metabolism

Cancer Investigation
Işil AlbenizEngin Bermek

Abstract

ADP-ribosylation of human serum proteins was studied in various groups of disorders. In most of these groups, the extent of ADP-ribosylation did not show a divergence from the group of normal controls. Neoplastic diseases revealed, however, a unique group, with more than fivefold increases in ADP-ribosylation levels over the other groups. Blood samples with high levels of ADP-ribosylation revealed, in general, increased serum NAD glycohydrolase activities and low levels of serum NAD.

References

Jan 1, 1992·International Journal of Clinical & Laboratory Research·F MalavasiS Roggero
Sep 30, 1986·Biochemical and Biophysical Research Communications·O SayhanE Bermek
Jan 1, 1985·Annual Review of Biochemistry·K Ueda, O Hayaishi
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Apr 15, 1994·Biochemical and Biophysical Research Communications·R NurtenE Bermek
Aug 18, 1993·Biochimica Et Biophysica Acta·U H KimN H An
Jan 1, 1995·Biochimie·M K JacobsonE L Jacobson

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Citations

Feb 19, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Başak VarolRüstem Nurten
Mar 12, 2005·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·L YalcintepeE Bermek

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