Adrenal function predicts demoralization after losses

Psychosomatics
S JacobsK Kim

Abstract

Stressful experiences can cause disturbances in the hypothalamic-pituitary-adrenocortical axis and the sympathetic-adrenomedullary system. The authors hypothesized that assessments of adrenal function made in the circumstances of stressful losses would predict outcome 1 or 2 years later. The authors collected 24-hour urinary free cortisol, serum cortisol, and 24-hour urinary catecholamines 2 months after intake and used these measures as predictors of depression, anxiety, hopelessness/helplessness, unresolved grief, self-rated health, and help-seeking behavior on follow-up at 13 and 25 months. Adrenal function in the circumstances of a loss predicted only demoralization scores (hopelessness/helplessness) on follow-up.

References

Mar 4, 1992·JAMA : the Journal of the American Medical Association·G P Chrousos, P W Gold
Dec 1, 1986·The British Journal of Medical Psychology·S JacobsP Charpentier
Jan 1, 1985·Psychotherapy and Psychosomatics·S JacobsS Schreiber
May 1, 1973·The British Journal of Psychiatry : the Journal of Mental Science·P E BornsteinE Robins

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Citations

Sep 26, 2003·Journal of Psychosomatic Research·Christina HalfordBengt Arnetz
Jul 14, 1999·Psychosomatics·P R Slavney
Jul 13, 2000·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·M H AntoniN Schneiderman
Apr 2, 2009·The British Journal of Psychiatry : the Journal of Mental Science·Mario F JuruenaAnthony J Cleare

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