Adrenal insufficiency due to ritonavir-triamcinolone drug-drug interaction without preceding Cushing's syndrome

International Journal of STD & AIDS
S NoeS Heldwein

Abstract

We present the case of a 58-year-old HIV-infected patient with adrenal insufficiency after local injection of triamcinolone, most likely due to drug-drug interaction with his ritonavir-boosted antiretroviral therapy (ART). This is the first case of adrenal insufficiency occurring without prior symptoms of Cushing's syndrome in a patient on a booster-containing ART. We want to draw attention to this seemingly rare, but potentially life-threatening medical condition that can occur even in short-term use of glucocorticoids in low doses in patients on booster-containing ART and summarize some considerations for management.

References

May 20, 1999·Annual Review of Pharmacology and Toxicology·F P Guengerich
Oct 6, 1999·AIDS·M E Hillebrand-HaverkortJ H ten Veen
Jan 26, 2005·Internal Medicine Journal·G SoldatosJ Stockigt
Nov 11, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Roshan RamanathanFrank Maldarelli
Jun 10, 2009·AIDS Research and Therapy·Kathryn DortChristopher C Moore
Jan 1, 2010·Clinical Pharmacology and Therapeutics·A A MathiasB P Kearney
May 13, 2010·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·D GrayM Klein
Jul 27, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Eynat KedemShimon Pollack
May 12, 2011·The Annals of Pharmacotherapy·Jonathan K Frankel, Clifford D Packer
Sep 17, 2011·Journal of the American Academy of Dermatology·Danielle LevineAmit Garg
Feb 14, 2012·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·C BerneckerH S Willenberg
May 1, 2012·The American Journal of the Medical Sciences·Nicole E AlbertRebecca Dougherty
Feb 27, 2013·BMJ Case Reports·Hannah Zelie Ruth McConkeyElizabeth Graham
Mar 20, 2013·Anesthesia Progress·Daniel E Becker
Mar 29, 2013·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Sarita D BoydScott R Penzak
Jun 29, 2013·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Marie-Christine BlondinOmar Serri
Aug 24, 2013·International Journal of STD & AIDS·Jill J HallStephen Shafran
Jun 5, 2014·Interdisciplinary Perspectives on Infectious Diseases·Sapna SadaranganiStacey Rizza
Feb 7, 2015·Journal of the American Pharmacists Association : JAPhA·Bernadette JakemanKarla Thornton
Apr 7, 2015·The Journal of Clinical Endocrinology and Metabolism·Leonie H A BroersenOlaf M Dekkers
Jan 14, 2016·The Journal of Clinical Endocrinology and Metabolism·Stefan R BornsteinDavid J Torpy
Sep 20, 2017·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Olivier VeilleuxEmily G McDonald
Nov 10, 2017·Endocrinology, Diabetes & Metabolism Case Reports·Gueorgui DubrocqNatella Rakhmanina

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