PMID: 9523526Apr 2, 1998Paper

Adrenalectomy for primary aldosteronism: long-term follow-up study in 29 patients

World Journal of Surgery
J SirénR Haapiainen

Abstract

Primary aldosteronism consists of a mixture of subgroups. The operative treatment is successful only in cases of aldosterone-producing neoplasia (and in rare cases of primary unilateral hyperplasia); all other cases should be treated medically. The aim of this study was to determine if aldosterone-producing neoplasia had been successfully differentiated from the other subgroups and the outcome of operative treatment. Altogether 29 patients with primary aldosteronism were operated on between January 1, 1979 and December 31, 1993. Patient charts were reviewed retrospectively. The follow-up data were collected from the patients' charts, and all patients were contacted to obtain recent blood pressure and serum potassium values. The patients were asked about symptoms related to hyperaldosteronism. If any suspicion of recidive aldosteronism was present, patients were carefully reexamined by hormonal tests and computed tomography (CT). A total of 27 patients had unilateral adenoma, 1 patient had hyperplasia, and 1 patient had an aldosterone-producing cortical carcinoma. There was no operative mortality or morbidity. The serum potassium level had normalized in all patients. Mean follow-up time was 76 months. One patient died during the...Continue Reading

Citations

Jan 27, 2007·Langenbeck's Archives of Surgery·Jacek ZiajaLech Cierpka
Feb 10, 2011·Reviews in Endocrine & Metabolic Disorders·Asterios Karagiannis
Apr 2, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yuji FukudomeMasatoshi Fujishima
Apr 2, 2009·Journal of Endocrinological Investigation·R CampagnacciM Guerrieri
Apr 28, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Y HoritaS Takishita
Jan 15, 2005·World Journal of Surgery·Andreas MeyerMatthias Behrend

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