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Adrenergic drug-receptor interaction in the presence of strontium (Sr++) in mammalian myocardium

Archives Internationales De Pharmacodynamie Et De Thérapie

Nov 1, 1975

Gerald O CarrierR P Ahlquist

PMID: 2115

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Abstract

The specificity of Ca++ for the interaction of beta adrenergic agonists with their receptors in rabbit right atrial muscle was evaluated. This was accomplished by substituting Ca++ by an equimolar concentration of Sr++. Dose-response curves which demonstrate the effect of norepinephrine...read more

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Myocardial Contraction
Propranolol
Strontium
Norepinephrine
Electrical Activity of Brain
Norepinephrine, (+, -)-Isomer
Agonists
Extracellular
Specimen Type - Cardiac Muscle
Calcium
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  • Adrenergic drug-receptor interaction in the presence of strontium (Sr++) in mammalian myocardium

    Archives Internationales De Pharmacodynamie Et De Thérapie

    Nov 1, 1975

    Gerald O CarrierR P Ahlquist

    PMID: 2115

    DOI:

    Abstract

    The specificity of Ca++ for the interaction of beta adrenergic agonists with their receptors in rabbit right atrial muscle was evaluated. This was accomplished by substituting Ca++ by an equimolar concentration of Sr++. Dose-response curves which demonstrate the effect of norepinephrine...read more

    Mentioned in this Paper

    Myocardial Contraction
    Propranolol
    Strontium
    Norepinephrine
    Electrical Activity of Brain

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