Aug 1, 1977

Adrenergic receptors in coronary arteries (author's transl)

Giornale italiano di cardiologia
F AmentaF Tassone


The relations between adrenergic nerve fibers and related receptors in the wall of the coronary arteries have been studied in man. On sections of these vessels morphological observations (H.E.) were carried out: histochemical staining of adrenergic mediators (Eranko reaction for norepinephrine, and Hillarp reaction for cathecolamines), and of beta-receptors by means of a beta-blocking fluorescent drug (pindolol-Visken LB 46). Our observations provide evidence of the presence of beta-receptors in the wall of the coronary arteries, but they are particularly concentrated in the periadventitial connective tissue, in the adventitia and in the intima-media transitional zone. Beta-adrenergic receptors are above all present in the most richly innervated part of the vascular wall, and are therefore in close rapport with adrenergic nerve fibers.

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Mentioned in this Paper

Tunica Intima
Accessory Atrioventricular Bundle
Blood Vessel
Nerve Fibers
Fluorescent stain

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