PMID: 8597447Dec 29, 1995Paper

Adrenocorticoid hormones and the development and expression of mammalian monogamy

Annals of the New York Academy of Sciences
C S CarterG P Chrousos

Abstract

Based on research with prairie voles, we hypothesize that the unusual patterns of reproduction and social behavior associated with mammalian monogamy may arise as a consequence of normal developmental exposure to high levels of glucocorticoids and/or other hormones of the HPA axis. Increased HPA activity could functionally inhibit some of the masculinizing processes expected during the perinatal period. We hypothesize that the unique behavioral, physiological, and anatomical changes associated with monogamy may reflect the adaptive consequences of reduced exposure to the masculinizing actions of HPG hormones, such as testosterone. Reproductively naive, unpaired adult prairie voles also show unusual patterns of adrenal activity, including a marked decline in corticosterone levels within minutes following exposure to novel animals of the opposite sex. In females, this decline in corticosterone may contribute to pair bonding, since corticosterone injections inhibit, and adrenalectomy is associated with a facilitation of pair bond formation. In males, corticosterone injections facilitate pair bonding and adrenalectomy has the opposite effect. In animals from established social pairs corticosterone levels also fluctuate according to...Continue Reading

References

Mar 1, 1977·The Quarterly Review of Biology·D G Kleiman
Jan 1, 1987·Physiology & Behavior·M Cohen-Parsons, C S Carter
Mar 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·G P ChrousosM B Lipsett
Jan 1, 1995·Neuroscience and Biobehavioral Reviews·C S CarterL L Getz
Jun 1, 1964·Medical Science·M I NEW
Dec 18, 1964·Science·J J CHRISTIAN, D E DAVIS

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Citations

Jun 13, 1998·Brain Research. Developmental Brain Research·C M McCormickS M Donohue
Oct 15, 1996·Proceedings of the National Academy of Sciences of the United States of America·A C DeVriesC S Carter
Sep 6, 2001·Hormones and Behavior·J G PfausS Centeno
Nov 5, 2013·Biological Psychiatry·Adam S Smith, Zuoxin Wang
Feb 24, 2012·Journal of Neuroendocrinology·W M KenkelC S Carter
Jul 25, 2006·Physiology & Behavior·Temitayo O Oyegbile, Catherine A Marler
Jan 7, 2015·Neurobiology of Stress·Annaliese K Beery, Daniela Kaufer
Jan 15, 1997·Annals of the New York Academy of Sciences·C S CarterL L Getz
Jan 15, 1997·Annals of the New York Academy of Sciences·R L RobertsC S Carter

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